Leaf Extract and Active Fractions of Dillenia pentagyna Roxb. Reduce In Vitro Human Cancer Cell Migration Via NF-κB Pathway

• Published in: Integrative cancer therapies Vol. 21; p. 15347354221128832
• Main Authors: De, Debapriya, Chowdhury, Priyanka, Panda, Sujogya Kumar, Ghosh, Utpal
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.01.2022; SAGE PUBLICATIONS, INC
• Subjects: Cadherins; Cancer; Cell adhesion & migration; Cell migration; Cell viability; Dillenia pentagyna; High-performance liquid chromatography; Metastases; Metastasis; N-Cadherin; NF-κB protein; Plant extracts; Vimentin; cell migration; NF-κB; Dillenia pentagyna; EMT; active fractions; MMPs

Background: Different parts of Dillenia pentagyna have long been used in traditional medicines to cure several diseases including cancer. However, the mechanism(s) of anti-cancer effects are still unknown. We aimed to elucidate the anti-metastatic potential of ethanolic extracts of leaves of D. pent...