Serum glycosidases in diabetes mellitus in relation to the retinopathy and to the length of the disease

• Published in: Clinica chimica acta Vol. 132; no. 1; pp. 23 - 27
• Main Authors: Serrano, MA, Reglero, A., Cabezas, J.A., Díez, L.C.García, Corrales, J.J., de Castro, S., Miralles, J.M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 31.07.1983
• Subjects: Adolescent; Adult; Diabetes Mellitus - enzymology; Diabetic Retinopathy - enzymology; Glycoside Hydrolases - blood; Humans; Middle Aged; Time Factors
• ISSN: 0009-8981; 1873-3492
• DOI: 10.1016/0009-8981(83)90229-2

The following glycosidase activities in sera have been studied: α- d-mannosidase, β- d-glucuronidase, N-acetyl-β- d-galactosaminidase, α- d-galactosidase, β- d-galactosidase, α- d-glucosidase, β- d-glucosidase and β- d-fucosidase, in diabetic patients in relation to the presence of microangiopathy, evident by retinopathy, and to the length of the disease. A significant increase of all the enzyme activities, except for α- d-galactosidase was found. These elevations were independent of the development of retinopathy and the duration of the diabetic process.