Tryptophan depletion in addictive behaviours
[...]the interplay between serotonin and cocaine may be altered after repeated cocaine administration, 4 a common manifestation in ‘real-world’ cocaine users. [...]using repeated measures ANOVAs, it was assumed that the effects of cocaine did not carry over across conditions. [...]it would have been...
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Published in | British journal of psychiatry Vol. 201; no. 1; pp. 73; author reply 73 - 73 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
Cambridge University Press
01.07.2012
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Subjects | |
Online Access | Get full text |
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Summary: | [...]the interplay between serotonin and cocaine may be altered after repeated cocaine administration, 4 a common manifestation in ‘real-world’ cocaine users. [...]using repeated measures ANOVAs, it was assumed that the effects of cocaine did not carry over across conditions. [...]it would have been clearer if the intervals between each condition were defined. [...]in the editorial by Nutt, 2 it is unclear as to the statement ‘It seems that this might be the case as in Cox et al's study lowering 5-HT function by tryptophan depletion led to a reduction in the actions of cocaine to release dopamine that was to some extent paralleled by a reduction in cocaine craving.’ |
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Bibliography: | SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Commentary-2 |
ISSN: | 0007-1250 1472-1465 |
DOI: | 10.1192/bjp.201.1.73 |