Unenhanced and Contrast-Enhanced MR Angiography and Perfusion Imaging for Suspected Pulmonary Thromboembolism

• Published in: American journal of roentgenology (1976) Vol. 208; no. 3; pp. 517 - 530
• Main Authors: Ohno, Yoshiharu, Yoshikawa, Takeshi, Kishida, Yuji, Seki, Shinichiro, Karabulut, Nevzat
• Format: Journal Article
• Language: English
• Published: United States 01.03.2017
• Subjects: Contrast Media; Diagnosis, Differential; Humans; Image Enhancement - methods; Magnetic Resonance Angiography - methods; Phlebography - methods; Pulmonary Embolism - diagnostic imaging; Reproducibility of Results; Sensitivity and Specificity; Venous Thrombosis - diagnostic imaging; CT; pulmonary thromboembolism; deep venous thrombosis; MRI; MR angiography
• ISSN: 0361-803X; 1546-3141
• DOI: 10.2214/ajr.16.17415

This article discusses the basics of unenhanced MR angiography (MRA) and MR venography (MRV), time-resolved contrast-enhanced (CE) MRA and dynamic first-pass CE perfusion MRI, and unenhanced and CE MRV, in addition to assessing the clinical relevance of these techniques for evaluating patients with suspected pulmonary thromboembolism and deep venous thrombosis. Since the 1990s, the efficacy of MRA or MRV and dynamic perfusion MRI for patients with suspected pulmonary thromboembolism and deep venous thrombosis has been evaluated. On the basis of the results of single-center trials, comprehensive MRI protocols, including pulmonary unenhanced and CE MRA, perfusion MRI, and MRV, promise to be safe and time effective for assessing patients with suspected pulmonary thromboembolism, although future multicenter trials are required to assess the real clinical value of MRI.