Some theoretic aspects of vascular degeneration

Certain theoretic aspects of vascular degeneration are presented. It is our general theory that the initiating factor in atherosclerosis is a series of molecular changes in the connective tissue of arteries, especially in elastin fibers. These molecular changes result in alterations in the physical...

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Bibliographic Details
Published inThe American journal of surgery Vol. 119; no. 5; pp. 548 - 552
Main Authors Reemtsma, Keith, Sandberg, Lawrence B, Greenfield, HH
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.1970
Subjects
Amino Acids - metabolism
Arteriosclerosis
Blood Circulation
Blood Flow Velocity
Computers
Connective Tissue - pathology
Elasticity
Elastin
Humans
Lipid Metabolism
Models, Chemical
Peptides - metabolism
Rheology
Vascular Diseases - pathology
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Summary:Certain theoretic aspects of vascular degeneration are presented. It is our general theory that the initiating factor in atherosclerosis is a series of molecular changes in the connective tissue of arteries, especially in elastin fibers. These molecular changes result in alterations in the physical properties of vessels, which make the arteries increasingly vulnerable to stress. The localization of the atherosclerotic process is determined primarily by rheologie factors, and the computer and graphic display system have provided new methods of studying the fluid dynamics of the vascular system.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0002-9610
1879-1883
DOI:10.1016/0002-9610(70)90173-X