Daily mocha coffee intake and psycho-cognitive status in non-demented non-smokers subjects with subcortical ischaemic vascular disease

• Published in: International journal of food sciences and nutrition Vol. 73; no. 6; pp. 821 - 828
• Main Authors: Fisicaro, Francesco, Lanza, Giuseppe, Pennisi, Manuela, Vagli, Carla, Cantone, Mariagiovanna, Falzone, Luca, Pennisi, Giovanni, Ferri, Raffaele, Bella, Rita
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 18.08.2022; Taylor & Francis Ltd
• Subjects: Activities of daily living; Age; Caffeine; Coffee; Cognition; Cognitive ability; cognitive disorders; Consumption; Dependent variables; dietary antioxidants; Education; emotions; executive dysfunction; Food science; half life; Ischemia; late-onset depressive disorder; nutrition; subcortical ischaemic vascular disease; Tobacco; tobacco smoking; Vascular diseases; subcortical ischaemic vascular disease; late-onset depressive disorder; dietary antioxidants; executive dysfunction; tobacco smoking; Caffeine
• ISSN: 0963-7486; 1465-3478; 1465-3478
• DOI: 10.1080/09637486.2022.2050999

Coffee intake has been recently associated with better cognition and mood in mild vascular cognitive impairment (mVCI). As tobacco can reduce the caffeine half-life, we excluded smokers from the original sample. Hamilton Depression Rating Scale (HDRS), mini-mental state examination (MMSE), Stroop Colour-Word Interference Test (Stroop), activities of daily living (ADL0) and instrumental ADL were the outcome measures. Significant differences were observed in higher consumption groups (moderate intake for HDRS; high intake for MMSE and Stroop) compared to the other groups, as well as in age and education. With age, education and coffee used as independent predictors, and HDRS, Stroop and MMSE as dependent variables, a correlation was found between age and both MMSE and Stroop, as well as between education and MMSE and between HDRS and Stroop; coffee intake negatively correlated with HDRS and Stroop. Higher coffee consumption was associated with better psycho-cognitive status among non-smokers with mVCI.