Biochemical evidence for the local synthesis and retention of fibronectin in the tissue of human placenta

1. 1.Human chorionic tissues were incubated with [ 14C]eucine and/or [ 14H]glucosamine, and fibronectin synthesis was examined. 2. 2. Radio-labeled fibronectin was detected in the tissue fraction of the incubation mixture, but not in the medium fraction, indicating that fibronectin is synthesized an...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of biochemistry Vol. 20; no. 1; pp. 113 - 116
Main Authors Hiroshi, Munakata, Norio, Hayashi, Yu, Yamaguchi, Yutaka, Aoyagi, Fumihiro, Ichida, Mamoru, Isemura
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 1988
Subjects
Carbon Radioisotopes
Chorionic Villi - metabolism
Chromatography, Affinity
Female
Fibronectins - biosynthesis
Fibronectins - isolation & purification
Glucosamine - metabolism
Humans
Leucine - metabolism
Placenta - metabolism
Pregnancy
Tritium
Online AccessGet full text

Cover

More Information
Summary:1. 1.Human chorionic tissues were incubated with [ 14C]eucine and/or [ 14H]glucosamine, and fibronectin synthesis was examined. 2. 2. Radio-labeled fibronectin was detected in the tissue fraction of the incubation mixture, but not in the medium fraction, indicating that fibronectin is synthesized and retained in the tissue. 3. 3. The glycopeptides derived from 3H-labeled fibronectin showed the lectin-binding characteristics similar to those from unlabeled placenta fibronectin, but different from those of plasma fibronectin.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0020-711X
DOI:10.1016/0020-711X(88)90021-3