Changes in nicotinamide adenine dinucleotide concentration of Bacillus cereus during growth

During the early stages of exponential growth, cultures of Bacillus cereus grown in a complex glucose medium contained relatively large amounts of nicotinamide-adenine dinucleotide which diminished rapidly with subsequent development. The reduction of intracellular nicotinamide-adenine dinucleotide...

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 124; no. 2; pp. 241 - 245
Main Author London, Jack
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 24.08.1966
Subjects
Aldehyde-Lyases - metabolism
Bacillus cereus - enzymology
Bacillus cereus - growth & development
Bacillus cereus - metabolism
Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism
Isocitrate Dehydrogenase - metabolism
NAD - metabolism
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Summary:During the early stages of exponential growth, cultures of Bacillus cereus grown in a complex glucose medium contained relatively large amounts of nicotinamide-adenine dinucleotide which diminished rapidly with subsequent development. The reduction of intracellular nicotinamide-adenine dinucleotide concentration appears to be related to the induction of a functional tricarboxylic acid cycle. The results presented here suggest that an inhibitor is produced during the growth of B. cereus which interferes with nicotinamide-adenine dinucleotide synthesis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0304-4165
0006-3002
1872-8006
DOI:10.1016/0304-4165(66)90185-1