Nicotinamide adenine dinucleotide in developing chick embryo

• Published in: Biochimica et biophysica acta Vol. 237; no. 2; pp. 329 - 334
• Main Authors: Shimoyama, Makoto, Shigehisa, Shoichi, Ueda, Iwao
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 18.05.1971
• Subjects: Aging; Alcohol Oxidoreductases; Animals; Chick Embryo - drug effects; Chick Embryo - growth & development; Chick Embryo - metabolism; Egg White; Egg Yolk; Female; Hydrogen-Ion Concentration; Liver - metabolism; NAD - metabolism; Niacinamide - metabolism; Niacinamide - pharmacology; Nicotinic Acids - metabolism; Nicotinic Acids - pharmacology; Ovalbumin - analysis; Pyridines - metabolism; Pyridines - pharmacology; Tryptophan - metabolism; Tryptophan - pharmacology
• ISSN: 0304-4165; 0006-3002; 1872-8006
• DOI: 10.1016/0304-4165(71)90326-6

The changes in NAD levels during the development of the chick embryo were investigated. Almost all NAD in the fertilized egg before incubation was localized in the white albumin, and NAD decreased rapidly during incubation. The hepatic NAD levels varied significantly during the development of the chick embryo. When several NAD precursors such as nicotinamide, nicotinic acid and tryptophan were injected into fertilized eggs before incubation, an increase of NAD in chick embryo was found in the first and middle periods of embryonic development, but no increase was observed in the latter stage.