Poisoning by DDT: Relation between Clinical Signs and Concentration in Rat Brain

The severity of signs of poisoning in rats after a single dose of DDT is directly proportional to the concentration of the compound in their brains. The concentrations associated with death after one large dose are about the same as those after many smaller doses.

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 142; no. 3598; pp. 1474 - 1476
Main Authors Dale, William E., Gaines, Thomas B., Hayes, Wayland J., Pearce, George W.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 13.12.1963
Subjects
Actinomycin
Antibodies
Antibody formation
Bacteriophages
Brain
Convulsions
DDT
Embryos
Histocytochemistry
Kidneys
Liver
Poisoning
Rats
Toxicology
RATS
DDT
BRAIN
HISTOCYTOCHEMISTRY
TOXICOLOGIC REPORT
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Summary:The severity of signs of poisoning in rats after a single dose of DDT is directly proportional to the concentration of the compound in their brains. The concentrations associated with death after one large dose are about the same as those after many smaller doses.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.142.3598.1474