Possible mechanism of hemostasis effected by electrocoagulation

Forty acute gastric ulcers were created in 10 rabbits. The bleeding was controlled by monopolar electrocoagulation in 20 ulcers, the remaining ulcers were left untreated as controls. Spontaneous intravascular thrombosis was precluded by heparinization. A histological assessment in the acute stage re...

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Bibliographic Details
Published inEndoscopy Vol. 16; no. 2; p. 43
Main Authors Wara, P, Berg, V, Jacobsen, N O, Casalnuovo, C, Amdrup, E
Format Journal Article
LanguageEnglish
Published Germany 01.03.1984
Subjects
Animals
Disease Models, Animal
Electrocoagulation
Endoscopy
Hemostasis
Peptic Ulcer Hemorrhage - pathology
Peptic Ulcer Hemorrhage - surgery
Rabbits
Stomach Ulcer - pathology
Stomach Ulcer - surgery
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Summary:Forty acute gastric ulcers were created in 10 rabbits. The bleeding was controlled by monopolar electrocoagulation in 20 ulcers, the remaining ulcers were left untreated as controls. Spontaneous intravascular thrombosis was precluded by heparinization. A histological assessment in the acute stage revealed significant morphological alterations in electrocoagulated ulcers, with fibrin deposition, decreased tissue stainability and swelling of the vessel walls, indicating heat-induced damage including cells of the vessel walls. An intravascular occlusive fibrin thrombosis demonstrated in all coagulated ulcers is suggested to be the probable mechanism of hemostasis.
ISSN:0013-726X
DOI:10.1055/s-2007-1018530