Retrieval of weak x-ray scattering using edge illumination

X-ray phase contrast imaging provides additional modes of image contrast compared to conventional attenuation-based x-ray imaging, thus providing additional structural and functional information about the sample. The edge-illumination (EI) technique has been used to provide attenuation, refraction,...

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Bibliographic Details
Published inOptics letters Vol. 43; no. 16; p. 3874
Main Authors Maughan Jones, Charlotte J, Vittoria, Fabio A, Olivo, Alessandro, Endrizzi, Marco, Munro, Peter R T
Format Journal Article
LanguageEnglish
Published United States 15.08.2018
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Summary:X-ray phase contrast imaging provides additional modes of image contrast compared to conventional attenuation-based x-ray imaging, thus providing additional structural and functional information about the sample. The edge-illumination (EI) technique has been used to provide attenuation, refraction, and scattering contrast in both biological and non-biological samples. However, the retrieval of low scattering signals by fitting a single Gaussian remains problematic, principally due to the inability of the EI system to achieve perfect dark-field illumination. We present a new retrieval method that fits three Gaussians, which successfully overcomes this limitation, and provide examples of the retrieval of such signals in highly absorbing, weakly scattering samples.
ISSN:1539-4794
DOI:10.1364/OL.43.003874