Hypogammaglobulinemia and hypoalbuminemia in neonates with ruptured omphaloceles and gastroschisis

• Published in: Journal of pediatric surgery Vol. 8; no. 3; pp. 353 - 359
• Main Authors: Gutenberger, James E., Miller, D.Lee, Dibbins, Albert W., Gitlin, David
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.1973
• Subjects: Abdominal Muscles - abnormalities; Agammaglobulinemia - etiology; Age Factors; Albumins - therapeutic use; Autopsy; Birth Weight; Blood; Blood Proteins - analysis; Child; Child, Preschool; Follow-Up Studies; Gestational Age; Hernia, Umbilical - blood; Hernia, Umbilical - complications; Humans; Immunoglobulin A - analysis; Immunoglobulin G - analysis; Immunoglobulin M - analysis; Infant; Infant, Newborn; Lymphoid Tissue - pathology; Rupture, Spontaneous - complications; Rupture, Spontaneous - congenital; Rupture, Spontaneous - drug therapy; Serum Albumin - analysis; Transferrin - analysis; Umbilical Cord

Infants born with ruptured omphaloceles have significantly decreased levels of total serum proteins, albumin, immunoglobulin G, and transferrin. The most likely explanation of these findings is the loss of serum into amniotic fluid from the peritoneal surfaces of the exposed viscera. The data indica...