Encrustation of a metal alloy urinary stent: a mechanistic investigation

• Published in: European urology Vol. 38; no. 2; p. 144
• Main Authors: Barbalias, G A, Bouropoulos, C, Vagenas, N V, Bouropoulos, N, Siablis, D, Liatsikos, E N, Karnabatidis, D, Koutsoukos, P G
• Format: Journal Article
• Language: English
• Published: Switzerland 01.08.2000
• Subjects: Alloys; Biocompatible Materials; Calcium Oxalate; Crystallization; Kinetics; Microscopy, Electron, Scanning; Prosthesis Failure; Stents
• ISSN: 0302-2838
• DOI: 10.1159/000020271

A section of a metal stent consisting mainly of tantalum coated partially by strongly adhering calcium oxalate monohydrate (COM) crystals was immersed in supersaturated solutions prepared from calcium chloride and sodium oxalate at 37 degrees C and ionic strength 0.15 M in NaCl. Abstract To investigate the kinetics of encrustation of a metall alloy urinary stent system in vitro by calcium oxalate and characterize the crystals forming from solutions supersaturated with respect to all calcium oxalate hydrates. The COM-coated stent mineralized upon immersion in the supersaturated solutions. The process was monitored with a calcium ion-selective electrode and the rates were measured at conditions of sustained solution supersaturation. COM crystals formed on the stent and the rate of COM crystal growth yielded a second-order dependence on the solution supersaturation. The deposition of COM crystals on the metal stents coated partially with COM crystals by adhesive forces was found to be most important for the acceleration of the encrustation process. The dependence of the rates on the solution supersaturation suggested absence of secondary nucleation and a surface-controlled process for the encrustation process.