Ectopic xanthomas in familial (type II) hypercholesterolemia

Xanthomas ordinarily occur in the skin and tendons of patients with severe hyperlipidemia. These xanthomas include xanthelasma, tuberous xanthoma, tendon xanthoma and eruptive xanthoma. Two patients with hypercholesterolemia are now described with xanthomas found in other locations, one deep in the...

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Bibliographic Details
Published inAtherosclerosis Vol. 37; no. 2; pp. 319 - 323
Main Authors Bhattacharyya, Ashim K., Preacher, A.B., Connor, William E.
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.10.1980
Subjects
Aged
Buttocks
Ectopic xanthoma
Familial hypercholesterolemia
Female
Humans
Hyperlipoproteinemia Type II - complications
Mechanism of formation
Mediastinum - pathology
Middle Aged
Xanthomatosis - complications
Xanthomatosis - diagnosis
Mechanism of formation
Familial hypercholesterolemia
Ectopic xanthoma
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Summary:Xanthomas ordinarily occur in the skin and tendons of patients with severe hyperlipidemia. These xanthomas include xanthelasma, tuberous xanthoma, tendon xanthoma and eruptive xanthoma. Two patients with hypercholesterolemia are now described with xanthomas found in other locations, one deep in the mediastinum and one in the muscles of the buttock. These masses simulated the occurrence of neoplastic tumors but on pathological and chemical examination proved to be typical xanthomata. Ectopic xanthomas should be considered in the differential diagnosis of masses in patients with familial hypercholesterolemia.
Bibliography:ObjectType-Case Study-3
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ISSN:0021-9150
1879-1484
DOI:10.1016/0021-9150(80)90018-0