Influence of flow amplitude on pulmonary resistance determined near zero flow

Pulmonary resistance, determined near zero flow by means of the isovolume technique, increases with the total amplitude of flow. This variation observed in healthy subjects at two frequencies, and documented also by other investigators, was simulated in a model study. The main factor responsible for...

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Bibliographic Details
Published inRespiration physiology Vol. 41; no. 1; pp. 61 - 69
Main Authors Clément, J., Bobbaers, H., Van De Woestijne, K.P.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.07.1980
Subjects
Adult
Airway Resistance
Airways elasticity
Amplitude dependence of pulmonary resistance
Computers
Female
Flow regime
Humans
Lung - physiology
Lung Compliance
Lung Volume Measurements
Male
Mathematics
Model study
Models, Biological
Respiration
Rohrer's constants
Model study
Flow regime
Amplitude dependence of pulmonary resistance
Rohrer's constants
Airways elasticity
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ISSN0034-5687
DOI10.1016/0034-5687(80)90023-7

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Summary:Pulmonary resistance, determined near zero flow by means of the isovolume technique, increases with the total amplitude of flow. This variation observed in healthy subjects at two frequencies, and documented also by other investigators, was simulated in a model study. The main factor responsible for the amplitude depdendence of pulmonary or airway resistance appears to be the asymmetrical elastic characteristics of the airways.
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ISSN:0034-5687
DOI:10.1016/0034-5687(80)90023-7