Incorporation of Heterologous Deoxyribonucleic Acid into Mammalian Cells

Particles containing large molecular heterologous deoxyribonucleic acid have been incorporated into strain L cells in suspension tissue culture. The particles are Feulgen-positive, they are fluorescent under ultraviolet light when stained with acridine orange, and they appear in both the nucleus and...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 133; no. 3450; pp. 381 - 382
Main Authors Bensch, Klaus G., King, Donald W.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 10.02.1961
Subjects
Acridines
Cell growth
Cell nucleus
Cytoplasm
DNA
Gelatins
L cells
Microscopy
Nucleic acids
Phenols
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Summary:Particles containing large molecular heterologous deoxyribonucleic acid have been incorporated into strain L cells in suspension tissue culture. The particles are Feulgen-positive, they are fluorescent under ultraviolet light when stained with acridine orange, and they appear in both the nucleus and cytoplasm in radioautographic preparations.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0036-8075
1095-9203
DOI:10.1126/science.133.3450.381