Vestibular ototoxicity in children: A retrospective study of 52 cases

We have carried out a study on 52 patients treated during childhood with potentially ototoxic drugs. The evaluation of vestibular function was carried out long after treatment. In most of the cases there was a parallelism between hearing and vestibular deficit. Manifest impairment of the vestibular...

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Bibliographic Details
Published inInternational journal of pediatric otorhinolaryngology Vol. 3; no. 3; pp. 195 - 198
Main Authors Camarda, V., Moreno, A.M., Boschi, V., Di Carlo, A., Spaziani, G., Saponara, M.
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.09.1981
Subjects
Adolescent
Adult
Aminoglycosides - adverse effects
Anti-Bacterial Agents - adverse effects
Child
Child, Preschool
Female
Hearing Disorders - chemically induced
Humans
Labyrinth Diseases - chemically induced
Male
Retrospective Studies
Streptomycin - adverse effects
Vestibular Function Tests
Vestibule, Labyrinth - drug effects
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Summary:We have carried out a study on 52 patients treated during childhood with potentially ototoxic drugs. The evaluation of vestibular function was carried out long after treatment. In most of the cases there was a parallelism between hearing and vestibular deficit. Manifest impairment of the vestibular function was demonstrated in 4 subjects, without remarkable hearing loss, who had previously been treated with streptomycin during childhood. Furthermore, in the case of 19 subjects, a considerable deambulation delay was noticed (in one case it revealed itself after the fourth year of life) which was attributable to a real injury to the vestibular structures. Finally, almost all examined subjects showed a dysfunction of equilibrium and a noticeable tendency to kinetopathy.
ISSN:0165-5876
1872-8464
DOI:10.1016/0165-5876(81)90002-1