The ionization constant of nicotinamide-adenine dinucleotide

The p K a of carefully purified oxidized nicotinamide adenine dinucleotide has been determined by potentiometric titration with sodium hydroxide at 25°. Values are reported for six ionic strengths up to 0.250. Extrapolation to zero ionic strength yields 3.88 ± 0.02 for the thermodynamic p K a .

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Bibliographic Details
Published inAnalytical biochemistry Vol. 29; no. 1; pp. 149 - 153
Main Authors Moore, C.E., Underwood, A.L.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1969
Subjects
Hydrogen-Ion Concentration
NAD
Osmolar Concentration
Potentiometry
Thermodynamics
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Summary:The p K a of carefully purified oxidized nicotinamide adenine dinucleotide has been determined by potentiometric titration with sodium hydroxide at 25°. Values are reported for six ionic strengths up to 0.250. Extrapolation to zero ionic strength yields 3.88 ± 0.02 for the thermodynamic p K a .
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0003-2697
1096-0309
DOI:10.1016/0003-2697(69)90018-9