A shigellosis outbreak associated with a sports festival at a kindergarten in Kitakyushu City, Japan

• Published in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Vol. 26; no. 11; pp. 1146 - 1151
• Main Authors: Kato, Hirofumi, Yahata, Yuichiro, Hori, Yuko, Fujita, Kagekiyo, Ooura, Noriko, Kido, Taeko, Yoshimoto, Katsuhiko, Matsui, Tamano, Izumiya, Hidemasa, Ohnishi, Makoto, Oishi, Kazunori
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2020
• Subjects: Kindergarten; Multiple-locus variable-number tandem-repeat analysis (MLVA); Outbreak; Shigella sonnei; RR; Shigella sonnei; PFGE; Outbreak; KCPHC; Multiple-locus variable-number tandem-repeat analysis (MLVA); Kindergarten; IDSC; FETP-J; MLVA; KCIES
• ISSN: 1341-321X; 1437-7780
• DOI: 10.1016/j.jiac.2020.06.005

Shigellosis cases have decreased gradually in Japan in recent years, but indigenous shigellosis outbreaks sometimes occur in childcare facilities. From national surveillance data, we identified a shigellosis outbreak involving a kindergarten. After detecting Shigella sonnei in Kitakyushu City, we conducted active case finding and epidemiological investigation in Kindergarten Z, including stool specimen collection and interviews. The stool specimens were cultured, and isolated strains were subjected to pulsed-field gel electrophoresis (PFGE) and multiple-locus variable-number tandem-repeat analysis (MLVA). Between September 1 and December 31, 2014, we identified 19 cases: 14 confirmed, 2 suspected, and 3 asymptomatic. Of the 19 cases, 16 were epidemiologically associated with Kindergarten Z (10 pupils, 5 family members, and 1 teacher). On October 19, a pupil with gastrointestinal illness participated in the kindergarten's sports festival, in which the pupils were split into “red” and “white” teams; the pupil in question belonged to the red team. Attack rates of the red and white teams were 8% (7/82) and 0% (0/108), respectively (relative risk, 10.5; 95% confidence interval, 1.3–82.1). PFGE patterns were identical or similar for the isolates in all 17 cases; 7 isolates were identical, and the others had one locus difference on MLVA. We concluded that contact during the sports festival could have been responsible for spread of the shigellosis outbreak at the kindergarten, although the infection source was not determined. It is vital to inform guardians immediately after detection of shigellosis cases that symptomatic pupils should not participate in activities such as sports festivals.