In vivo time-gated diffuse correlation spectroscopy at quasi-null source-detector separation

• Published in: Optics letters Vol. 43; no. 11; p. 2450
• Main Authors: Pagliazzi, M, Sekar, S Konugolu Venkata, Di Sieno, L, Colombo, L, Durduran, T, Contini, D, Torricelli, A, Pifferi, A, Mora, A Dalla
• Format: Journal Article
• Language: English
• Published: United States 01.06.2018
• Subjects: Adult; Blood Flow Velocity - physiology; Female; Humans; Optical Fibers; Photons; Scattering, Radiation; Spectrum Analysis - methods

We demonstrate time domain diffuse correlation spectroscopy at quasi-null source-detector separation by using a fast time-gated single-photon avalanche diode without the need of time-tagging electronics. This approach allows for increased photon collection, simplified real-time instrumentation, and...