Effects of low temperature on RNA metabolism in different cell lines

The effects of low temperatures on RNA synthesis have been investigated in six different monolayer cell lines. Substantial differences have been observed in the behaviour of the cell lines during and after treatment at 4 °C. It is thus likely that techniques involving 4 °C treatment are not generall...

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Bibliographic Details
Published inExperimental cell research Vol. 99; no. 1; pp. 200 - 204
Main Authors Sensky, T.E., Haines, M.E., Rees, K.R.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.1976
Subjects
Cell Line
Cell Nucleolus - metabolism
Cell Transformation, Neoplastic
Cold Temperature
HeLa Cells
RNA - biosynthesis
Subcellular Fractions - metabolism
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Summary:The effects of low temperatures on RNA synthesis have been investigated in six different monolayer cell lines. Substantial differences have been observed in the behaviour of the cell lines during and after treatment at 4 °C. It is thus likely that techniques involving 4 °C treatment are not generally applicable to pulse-chase studies of RNA biosynthesis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0014-4827
1090-2422
DOI:10.1016/0014-4827(76)90700-X