To Induce Immune Reconstitution Inflammatory Syndrome or Suppress It: The Spectrum of Mycobacterium genavense in the Antiretroviral Era

Abstract Mycobacterium  genavense is a challenging opportunistic pathogen to diagnose and manage in patients with human immunodeficiency virus (HIV). Persistent immunosuppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe 3 cases o...

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Published inClinical infectious diseases Vol. 72; no. 2; pp. 315 - 318
Main Authors Manion, Maura, Lynn, Niamh, Pei, Luxin, Hammoud, Dima A, Laidlaw, Elizabeth, Roby, Gregg, Metzger, Dorinda, Mejia, Yolanda, Lisco, Andrea, Zelazny, Adrian, Holland, Steve, Vachon, Marie-Louise, Scherer, Matthew, Bergin, Colm, Sereti, Irini
Format Journal Article
LanguageEnglish
Published US Oxford University Press 27.01.2021
Subjects
HIV Infections - drug therapy
Humans
Immune Reconstitution Inflammatory Syndrome
Mycobacterium
Nontuberculous Mycobacteria
HIV
IRIS
Mycobacterium genavense
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Summary:Abstract Mycobacterium  genavense is a challenging opportunistic pathogen to diagnose and manage in patients with human immunodeficiency virus (HIV). Persistent immunosuppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe 3 cases of M. genavense in patients with HIV representing the spectrum between disease burden and strength of immune response.
Bibliography:ObjectType-Article-1
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ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa753