Analysis of sagittal profile of spine using 3D ultrasound imaging: a phantom study and preliminary subject test

• Published in: Computer methods in biomechanics and biomedical engineering. Vol. 8; no. 3; pp. 232 - 244
• Main Authors: Lee, Timothy Tin-Yan, Cheung, James Chung-Wai, Law, Siu-Yu, To, Michael Kai Tsun, Cheung, Jason Pui Yin, Zheng, Yong-Ping
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 03.05.2020
• Subjects: 3D ultrasound imaging; Cobb's angle; sagittal balance; Spine; spinous process
• ISSN: 2168-1163; 2168-1171
• DOI: 10.1080/21681163.2019.1566025

Radiographic Cobb's angle is the gold standard for evaluation of spinal curvature, however, X-ray is ionising. In contrast, ultrasound is non-ionising and inexpensive. However, no study has reported the reliability and accuracy of ultrasound on sagittal curvature analysis. Ultrasound and X-ray scanning were conducted on 16 sets of spine phantoms with different deformities. Intra-rater and inter-rater reliability, correlations, mean absolute differences (MAD) and linear regression of ultrasound spinous process angles (USSPA), X-ray spinous process angles (XSPA) and X-ray Cobb's angles (XCA) together with the intra-operator reliability of USSPA were investigated. In addition, USSPA and XCA of five AIS subjects were obtained using the ultrasound system. In the phantom study, excellent intra-rater and inter-rater reproducibility for the three angles and excellent intra-operator reproducibility for USSPA were demonstrated. Good to moderate or better correlations were obtained among the angles. All three angles indicated positive linear relationships with MAD ≤ 6.0°. The results of the preliminary study demonstrated a high intra-reliability for the ultrasound measurements. The measured difference between the USSPA and XCA methods was 6.3° ± 5.4°. The results showed that ultrasound is feasible for measuring sagittal curvature and has the potential for monitoring the curve progression and evaluating sagittal spinal profiles.