Retention of pseudouridine and 4-amino-5-imidazole carboxamide in uraemia

Concentrations of pseudouridine and 4-amino-5-imidazole carboxamide have been estimated in uraemic plasma where levels were found higher than in normals. There was a significant correlation between plasma pseudouridine and urea. Abnormal amounts of N-methyl-2-pyridone-5-carboxamide were also detecte...

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Bibliographic Details
Published inClinica chimica acta Vol. 20; no. 3; pp. 407 - 411
Main Author Asatoor, A.M.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.1968
Subjects
Chromatography, Paper
Humans
Imidazoles - blood
Nicotinic Acids - blood
Nucleosides - blood
Renal Dialysis
Urea - blood
Uremia - blood
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Summary:Concentrations of pseudouridine and 4-amino-5-imidazole carboxamide have been estimated in uraemic plasma where levels were found higher than in normals. There was a significant correlation between plasma pseudouridine and urea. Abnormal amounts of N-methyl-2-pyridone-5-carboxamide were also detected in uraemic plasma. Analysis before and after haemodialysis showed that pseudouridine and N-methyl-2-pyridone-5-carboxamide are reduced approximately to the same degree as urea.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(68)90297-0