Porcine valve durability: A comparison between Hancock standard and Hancock II bioprostheses

• Published in: The Annals of thoracic surgery Vol. 60; no. 2 Suppl; pp. S216 - S220
• Main Authors: Bortolotti, Uberto, Milano, Aldo, Mossuto, Eugenio, Mazzaro, Enzo, Thiene, Gaetano, Casarotto, Dino
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.08.1995
• Subjects: Actuarial Analysis; Aged; Aortic Valve - surgery; Bioprosthesis; Female; Heart Valve Prosthesis - mortality; Humans; Male; Middle Aged; Mitral Valve - surgery; Postoperative Complications; Prosthesis Failure; Survival Rate
• ISSN: 0003-4975; 1552-6259
• DOI: 10.1016/0003-4975(95)00255-J

Two series of patients who received a Hancock standard (HS) (1970 to 1983) and a Hancock II (HID (1983 to 1992) porcine bioprosthesis were reviewed to compare bioprosthetic durability. Patients with HS porcine bioprostheses (n = 769) differed from those with HII bioprostheses mostly in mean age at operation (47 ± 12 versus 62 ± 9 years; p < 0.001); the latter prosthesis was implanted mostly in patients older than 50 years. At 8 years after operation, actuarial survival was 57% ± 4% after aortic, 61% ± 3% after mitral, and 39% ± 7% after mitral-aortic valve replacement with the HS bioprosthesis; actuarial survival was 51% ± 9% after aortic, 66% ± 6% after mitral, and 49% ± 10% after mitral and aortic valve replacement with an HII bioprosthesis. No cases of structural deterioration of HII bioprostheses were observed at 8 years in any patients. Actuarial freedom from structural valve deterioration was 78% ± 4% after aortic, 88% ± 3% after mitral, and 79% ± 7% after mitral-aortic valve replacement with an HS bioprosthesis at 8 years. In all patients greater than 50 years of age, actuarial freedom from structural valve deterioration at 8 years was 90% ± 3% in patients with an HS bioprosthesis and 100% in those with an HII bioprosthesis (p = 0.08). A trend to an improved durability of the HII bioprosthesis compared with the HS was observed during the first 8 postoperative years. Because these results could be influenced partly by the age difference in the two series of patients, a longer follow-up is needed to confirm these data.