Resistance to Tonic-Clonic seizures after amygdaloid kindling in cats

Tonic-Clonic seizures induced by amygdaloid stimulation in cats are followed by a period during which the threshold for the induction of subsequent seizure activity is elevated (postictal refractory period). The duration of this change is 2 to 5 h in kindled cats and 30 to 60 min in nonkindled cats....

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Bibliographic Details
Published inExperimental neurology Vol. 69; no. 2; pp. 239 - 246
Main Authors Stock, G., Klimpel, L., Sturm, V., Schlör, K.-H.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.08.1980
Subjects
Amygdala - physiology
Animals
Blood Pressure
Cats
Electric Stimulation
Electroencephalography
Evoked Potentials
Heart Rate
Male
Neural Conduction
Refractory Period, Electrophysiological
Seizures - physiopathology
Seizures - psychology
EEG
PRP
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Summary:Tonic-Clonic seizures induced by amygdaloid stimulation in cats are followed by a period during which the threshold for the induction of subsequent seizure activity is elevated (postictal refractory period). The duration of this change is 2 to 5 h in kindled cats and 30 to 60 min in nonkindled cats. Arterial blood pressure, heart rate, and cortical and subcortical EEG recordings were taken as indices of seizure activity. Using these parameters, especially the hemodynamic changes, it was shown that the amygdaloid complex is not functionally inactive during the postictal refractory period but rather shows excitability which compares with prekindling values.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0014-4886
1090-2430
DOI:10.1016/0014-4886(80)90207-1