Preventive effects of N‐acetyl‐l‐cysteine against imidacloprid intoxication on Bombyx mori larvae

Imidacloprid, a widely used neonicotinoid insecticide, is toxic to silkworm (Bombyx mori). To explore whether N‐acetyl‐l‐cysteine (NAC) has an effect on preventing silkworm (B. mori) from toxification caused by imidacloprid, we fed the fifth‐instar larvae with mulberry leaves dipped in 200 mg/L NAC...

Full description

Saved in:
Bibliographic Details
Published inArchives of insect biochemistry and physiology Vol. 99; no. 2; pp. e21497 - n/a
Main Authors Gao, Hui‐Ju, Sun, Yong‐Liang, Song, Gui‐Zhen, Su, Bin, Zhang, Meng‐Meng, Ren, Chun‐Jiu, Wang, Yan‐Wen
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.10.2018
Subjects
Acetylcysteine
antioxidant enzymes activities
Antioxidants
Body weight
Bombyx mori
Catalase
Cysteine
Enzymes
Exposure
Feed efficiency
Glutathione
growth and development
Imidacloprid
Insecticides
Intoxication
Larvae
Malondialdehyde
Midgut
N‐acetyl‐l‐cysteine
Peroxide
Restoration
Silkworms
Superoxide dismutase
Survival
Bombyx mori
N-acetyl-l-cysteine
antioxidant enzymes activities
growth and development
imidacloprid
Online AccessGet full text

Cover

More Information
Summary:Imidacloprid, a widely used neonicotinoid insecticide, is toxic to silkworm (Bombyx mori). To explore whether N‐acetyl‐l‐cysteine (NAC) has an effect on preventing silkworm (B. mori) from toxification caused by imidacloprid, we fed the fifth‐instar larvae with mulberry leaves dipped in 200 mg/L NAC solution before exposing in imidacloprid, and investigated the silkworm growth, survival rate, feed efficiency, cocoon quality, and the activities of antioxidant enzymes in midgut. The results showed that addition of NAC could significantly increase body weight, survival rate, and feed efficiency of imidacloprid poisoned silkworm larvae (P < 0.05), as well as cocoon mass, cocoon shell mass, and the ratio of cocoon shell (P < 0.05). Furthermore, it could significantly promote the activities of the antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxide in the midgut of fifth‐instar larvae under imidacloprid exposure at the late stage of treatment. In addition, it also could downregulate the malondialdehyde content. The results of our findings proved that the added NAC may have some beneficial effects on protection or restoration of antioxidant balance in imidacloprid exposed larvae.
ISSN:0739-4462
1520-6327
DOI:10.1002/arch.21497