Let Food Be Thy Medicine: Diet, Nutrition, and Biomarkers’ Risk of Alzheimer’s Disease

Epidemiological evidence linking diet—one of the most important modifiable lifestyle factors—and risk of Alzheimer’s disease (AD)—the most common cause of dementia—is rapidly increasing. However, the biological mechanisms underlying the relationship between dietary nutrients, brain aging, and risk o...

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Bibliographic Details
Published inCurrent nutrition reports Vol. 4; no. 2; pp. 126 - 135
Main Authors Mosconi, Lisa, McHugh, Pauline F.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.06.2015
Subjects
Cardiology
Clinical Nutrition
Diabetes
Health Promotion and Disease Prevention
Medicine
Medicine & Public Health
Neurological Disease and Cognitive Function (G Logroscino
Oncology
Section Editor
Topical Collection on Neurological Disease and Cognitive Function
Brain aging
Brain imaging
Alzheimer’s disease
Nutrition
Diet
Magnetic resonance imaging
Normal aging
Plasma nutrients
Biomarkers
Preclinical
Positron emission tomography
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Summary:Epidemiological evidence linking diet—one of the most important modifiable lifestyle factors—and risk of Alzheimer’s disease (AD)—the most common cause of dementia—is rapidly increasing. However, the biological mechanisms underlying the relationship between dietary nutrients, brain aging, and risk of AD are largely unexplored. Recent studies using brain imaging and biological markers of AD have begun to clarify how diet and nutrition modulate risk of AD in cognitively normal individuals, especially those at increased genetic risk. Such knowledge is critical prior to implementing dietary recommendations for prevention and treatment of disease.
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ISSN:2161-3311
2161-3311
DOI:10.1007/s13668-014-0111-5