Prevalence and factors associated with urinary incontinence in females with cystic fibrosis: An Italian single‐center cross‐sectional analysis
Background Individuals with cystic fibrosis (CF) are deemed to have a higher risk of developing urinary incontinence (UI), likely due to repeated increasing pressure on the pelvic floor. We aimed to determine the prevalence of female UI in a large CF referral center, and to assess the association be...
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Published in | Pediatric pulmonology Vol. 57; no. 1; pp. 132 - 141 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Wiley Subscription Services, Inc
01.01.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Background
Individuals with cystic fibrosis (CF) are deemed to have a higher risk of developing urinary incontinence (UI), likely due to repeated increasing pressure on the pelvic floor. We aimed to determine the prevalence of female UI in a large CF referral center, and to assess the association between UI and severity of CF disease.
Methods
We consecutively recruited female patients regularly attending our CF center, aged ≥6 years and with a confirmed diagnosis of CF. Prevalence, severity, and impact of UI were assessed by administering two validated questionnaires. Relationship between variables was evaluated by means of multiple correspondence analysis, whereas a logistic model was fitted to capture the statistical association between UI and independent variables.
Results
UI was present in 51/153 (33%, 95% confidence interval [CI]: 26%–41%) females. Among children and adolescents, the prevalence was 12/82 (15%, 95% CI: 8%–25%) whereas among adults was 39/71 (55%, 95% CI: 43%–67%). The only explanatory variable associated with UI was age, with children presenting the lowest risk (odds ratio, 0.32; 95% CI: 0.05–0.93). Females presenting low or high nutritional status show higher profile risk of having UI.
Conclusions
Stress UI is a common complication in females with CF since childhood. Although it frequently occurs in older patients with a more severe phenotype, much attention should be paid to adults and to their nutritional status. |
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Bibliography: | Alessandra Mariani and Simone Gambazza contributed equally as first author. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 8755-6863 1099-0496 |
DOI: | 10.1002/ppul.25723 |