Chemical constituents from the water-soluble fraction of wild Sargentodoxa cuneata

• Published in: Chinese journal of natural medicines Vol. 10; no. 2; pp. 115 - 118
• Main Authors: TANG, Jian, MA, Rui-Li, OUYANG, Zhen, CHEN, Hai-Sheng
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.03.2012
• Subjects: (+)-Syringin; (−)-Lyoniresinol-9-O-β-D-glucoside; chemical composition; chromatography; electrospray ionization mass spectrometry; glycosides; nuclear magnetic resonance spectroscopy; Sargentodoxa cuneata; Sargentol; silica gel; spectral analysis; water solubility; Sargentol; (−)-Lyoniresinol-9-O-β-D-glucoside; Sargentodoxa cuneata; (+)-Syringin
• ISSN: 1875-5364; 1875-5364
• DOI: 10.3724/SP.J.1009.2012.00115

To study the chemical constituents from the water-soluble fraction of wild Sargentodoxa cuneata. The compounds were isolated by silica gel and HW-40C column chromatography. Their structures were elucidated on the basis of spectral analysis of ESI-MS and NMR. Eight known glycosides were isolated and identified as (−)-lyoniresinol-9-O-β-D-glucoside (1), (+)-lyoniresinol-9-O-β-D-glucoside (2), (−)-lyoniresinol-9′-O-β-D-glucoside (3), (+)-syringaresinol-4-O-β-D-glucoside (4), androsin (5), (+)-syringin (6), sargentol (7) and daucosterol (8). Compounds 1, 3 and 6 were isolated from this plant for the first time, and constituents of the water-soluble parts of wild S. cuneata were studied systematically for the first time.