Biosynthesis of Streptococcal Cell Walls: A Rhamnose Polysaccharide

Protoplast membranes from Streptococcus pyogenes incorporated rhamnose into a preexisting polysaccharide when incubated with thymidine diphosphate rhamnose-C$^{14}$. This polysaccharide, when extracted from the membranes, did not give a precipitin reaction with group A antisera, but could be copreci...

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Published inScience (American Association for the Advancement of Science) Vol. 140; no. 3565; pp. 400 - 401
Main Authors Zeleznick, L. D., Boltralik, J. J., Barkulis, S. S., Smith, C., Heymann, H.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 26.04.1963
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Summary:Protoplast membranes from Streptococcus pyogenes incorporated rhamnose into a preexisting polysaccharide when incubated with thymidine diphosphate rhamnose-C$^{14}$. This polysaccharide, when extracted from the membranes, did not give a precipitin reaction with group A antisera, but could be coprecipitated with added group A polysaccharide by acetone. It is presumed to be a precursor to group specific polysaccharide of the streptococcal cell wall.
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.140.3565.400