The Microbiota Regulates Immunity and Immunologic Diseases in Dogs and Cats

The complex commensal microbiota found on body surfaces controls immune responses and the development of allergic and inflammatory diseases. New genetic technologies permit investigators to determine the composition of the complex microbial populations found on these surfaces. Changes in the microbi...

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Bibliographic Details
Published inThe Veterinary clinics of North America. Small animal practice Vol. 48; no. 2; p. 307
Main Authors Tizard, Ian R, Jones, Sydney W
Format Journal Article
LanguageEnglish
Published United States 01.03.2018
Subjects
Autoimmunity
Hygiene hypothesis
Microbiota
Dysbiosis
Atopic dermatitis
Allergies
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Summary:The complex commensal microbiota found on body surfaces controls immune responses and the development of allergic and inflammatory diseases. New genetic technologies permit investigators to determine the composition of the complex microbial populations found on these surfaces. Changes in the microbiota (dysbiosis) as a result of antibiotic use, diet, or other factors thus influence the development of many diseases in the dog and cat. The most important of these include chronic gastrointestinal disease; respiratory allergies, such as asthma; skin diseases, especially atopic dermatitis; and some autoimmune diseases.
ISSN:1878-1306
DOI:10.1016/j.cvsm.2017.10.008