Galactorrhea-amenorrhea: psychological interaction with neuroendocrine function

Further substantiation of the interaction between psychological disease and the onset of galactorrhea-amenorrhea is presented in women who underwent intensive psychometric and neuroendocrine evaluation prior to the use of the dopamine against 2-Br-alpha-ergocryptine (CB-154). Normalization of a prev...

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Bibliographic Details
Published inAmerican journal of obstetrics and gynecology Vol. 125; no. 6; p. 859
Main Authors Zacur, H A, Chapanis, N P, Lake, C R, Ziegler, M, Tyson, J E
Format Journal Article
LanguageEnglish
Published United States 15.07.1976
Subjects
Adult
Amenorrhea - drug therapy
Amenorrhea - etiology
Bromocriptine - pharmacology
Bromocriptine - therapeutic use
Clinical Trials as Topic
Contraceptives, Oral
Dopamine Antagonists
Dopamine beta-Hydroxylase - blood
Female
Galactorrhea - drug therapy
Galactorrhea - etiology
Humans
Lactation Disorders - etiology
Norepinephrine - blood
Pregnancy
Prolactin - metabolism
Psychological Tests
Psychophysiologic Disorders
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Summary:Further substantiation of the interaction between psychological disease and the onset of galactorrhea-amenorrhea is presented in women who underwent intensive psychometric and neuroendocrine evaluation prior to the use of the dopamine against 2-Br-alpha-ergocryptine (CB-154). Normalization of a previously distorted psychometric test profile in each woman was accompanied by a profound decline in prolactin and an unexpected alteration in the peripheral concentrations of norepinephrine and dopamine-beta-hydroxylase. Cesation of galactorrhea and resumption of menses were observed in each instance.
ISSN:0002-9378
DOI:10.1016/0002-9378(76)90863-2