Cystoid macular edema as the primary sign of neurosyphilis

A 34-year-old man had a six-month history of bilateral visual loss that was secondary to cystoid macular edema, which was assumed to be secondary to neurosyphilis on the basis of cerebrospinal fluid serology, cell count, and protein. Good visual acuity was recovered with systemic corticosteroids onl...

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Bibliographic Details
Published inAmerican journal of ophthalmology Vol. 88; no. 1; p. 28
Main Authors Martin, N F, Fitzgerald, C R
Format Journal Article
LanguageEnglish
Published United States 01.07.1979
Subjects
Administration, Oral
Adult
Cerebrospinal Fluid - cytology
Cerebrospinal Fluid Proteins - analysis
Chorioretinitis - diagnosis
Chorioretinitis - drug therapy
Chorioretinitis - etiology
Edema - diagnosis
Edema - drug therapy
Edema - etiology
Fluorescein Angiography
Follow-Up Studies
Humans
Injections, Intramuscular
Macula Lutea
Male
Neurosyphilis - complications
Neurosyphilis - diagnosis
Neurosyphilis - drug therapy
Penicillin G Benzathine - administration & dosage
Penicillin G Benzathine - therapeutic use
Prednisone - administration & dosage
Prednisone - therapeutic use
Syphilis Serodiagnosis
Vision Disorders - etiology
Visual Acuity
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Summary:A 34-year-old man had a six-month history of bilateral visual loss that was secondary to cystoid macular edema, which was assumed to be secondary to neurosyphilis on the basis of cerebrospinal fluid serology, cell count, and protein. Good visual acuity was recovered with systemic corticosteroids only after they were used in combination with antitreponemal therapy. This is the first report, to the best of our knowledge, of cystoid macular edema as the primary sign of neurosyphilis documented by fluorescein angiography.
ISSN:0002-9394
DOI:10.1016/0002-9394(79)90747-5