Systemic Mastocytosis in an African Fat-Tail Gecko (Hemitheconyx caudicinctus)

A 3-year-old African fat-tail gecko (Hemitheconyx caudicinctus) suddenly became lethargic and died 2 days later. Necropsy examination revealed a submandibular mass and discolouration of the liver, kidneys and skeletal muscles of the tail. Microscopical evaluation revealed neoplastic mast cells in th...

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Bibliographic Details
Published inJournal of comparative pathology Vol. 151; no. 1; pp. 130 - 134
Main Authors Irizarry Rovira, A.R., Holzer, T.R., Credille, K.M.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.07.2014
Subjects
Animals
electron microscopy
Female
gecko
immunohistochemistry
Lizards
Mast Cells - pathology
Mastocytosis, Systemic - pathology
Mastocytosis, Systemic - veterinary
systemic mastocytosis
electron microscopy
gecko
immunohistochemistry
systemic mastocytosis
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Summary:A 3-year-old African fat-tail gecko (Hemitheconyx caudicinctus) suddenly became lethargic and died 2 days later. Necropsy examination revealed a submandibular mass and discolouration of the liver, kidneys and skeletal muscles of the tail. Microscopical evaluation revealed neoplastic mast cells in the skin, liver, kidneys, skeletal muscles, bones, spleen, uterus, ovaries and lungs. Exfoliative cytological, histopathological and ultrastructural features were consistent with systemic mastocytosis. Neoplastic proliferative disorders of mast cells are rare in reptiles and this is the first report of mast cell neoplasia in geckos. [Display omitted]
Bibliography:ObjectType-Case Study-2
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ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2014.03.006