Assessment of licit and illicit drugs consumption during pregnancy by Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry (UHPLC-HRMS) target screening in Mexican women hair

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 211; p. 114607
• Main Authors: Marchei, Emilia, Rotolo, Maria Concetta, Mannocchi, Giulio, Capomassi, Angelica, Gómez-Ruiz, Larissa-María, Acosta-López, Aracely, Ramos-Gutiérrez, Ruth-Yesica, Varela-Busaka, Mary-Buhya, Pichini, Simona, García-Algar, Óscar
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 20.03.2022
• Subjects: Biomarkers; Chromatography, High Pressure Liquid - methods; Female; Hair - chemistry; Hair testing; Humans; Illicit Drugs - analysis; Mass Spectrometry; Pregnancy; Psychoactive substances; Substance Abuse Detection - methods; Substance-Related Disorders; UHPLC-HRMS; Pregnancy; Psychoactive substances; Biomarkers; Hair testing; UHPLC-HRMS

•UHPLC-HRMS method was optimized to screen xenobiotics in hair samples.•The method was successfully applied to hair samples from Mexican pregnant women.•Hair testing objectively assesses gestational drugs consumption.•Methamphetamine and THC were the most prevalent drugs in the examined cohort. Subs...