Tailoring the physicochemical properties of nanomaterials for immunomodulation

Nanomaterial physicochemical properties affect their immunomodulation. Here, size, surface charge, shape, rigidity and surface chemical composition of nanomaterials are discussed for understanding nanomaterials-induced immune responses. [Display omitted] Immunomodulation is poised to revolutionize t...

Full description

Saved in:
Bibliographic Details
Published inAdvanced drug delivery reviews Vol. 180; p. 114039
Main Authors Deng, Junjie, Wang, Jilong, Shi, Jiaqi, Li, Hongjun, Lu, Mingqin, Fan, Zhiyuan, Gu, Zhen, Cheng, Hao
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.2022
Subjects
Complement
Drug delivery
Drug Delivery Systems
Humans
Immunoengineering
Immunologic Factors - chemistry
Immunotherapy
Nanomaterials
Nanoparticles - chemistry
Nanomaterials
Complement
Drug delivery
Immunotherapy
Immunoengineering
Online AccessGet full text

Cover

Abstract Nanomaterial physicochemical properties affect their immunomodulation. Here, size, surface charge, shape, rigidity and surface chemical composition of nanomaterials are discussed for understanding nanomaterials-induced immune responses. [Display omitted] Immunomodulation is poised to revolutionize the treatment of cancer, autoimmune diseases, and many other inflammation-related disorders. The immune system in these conditions can be either activated or suppressed by nanocarriers loaded with bioactive molecules. Although immunomodulation via these therapeutics has long been recognized, and a broad range of nanocarriers have been designed to accommodate varied usages, less studies have focused on the effects of nanomaterial physicochemical properties on immune responses, especially the immunity altered by nanocarrier materials alone. Conclusions are sometimes seemly inconsistent due to the complexities of nanomaterials and the immune system. An in-depth understanding of the nanocarrier-induced immune responses is essential for clinical applications. In this review, we summarize recent studies of the immune responses influenced by nanomaterial physicochemical properties with an emphasis on the intrinsic features of nanomaterials that modulate the innate and adaptive immunities. We then provide our perspectives on the design of nanomaterials for immunomodulation.
AbstractList Immunomodulation is poised to revolutionize the treatment of cancer, autoimmune diseases, and many other inflammation-related disorders. The immune system in these conditions can be either activated or suppressed by nanocarriers loaded with bioactive molecules. Although immunomodulation via these therapeutics has long been recognized, and a broad range of nanocarriers have been designed to accommodate varied usages, less studies have focused on the effects of nanomaterial physicochemical properties on immune responses, especially the immunity altered by nanocarrier materials alone. Conclusions are sometimes seemly inconsistent due to the complexities of nanomaterials and the immune system. An in-depth understanding of the nanocarrier-induced immune responses is essential for clinical applications. In this review, we summarize recent studies of the immune responses influenced by nanomaterial physicochemical properties with an emphasis on the intrinsic features of nanomaterials that modulate the innate and adaptive immunities. We then provide our perspectives on the design of nanomaterials for immunomodulation.
Nanomaterial physicochemical properties affect their immunomodulation. Here, size, surface charge, shape, rigidity and surface chemical composition of nanomaterials are discussed for understanding nanomaterials-induced immune responses. [Display omitted] Immunomodulation is poised to revolutionize the treatment of cancer, autoimmune diseases, and many other inflammation-related disorders. The immune system in these conditions can be either activated or suppressed by nanocarriers loaded with bioactive molecules. Although immunomodulation via these therapeutics has long been recognized, and a broad range of nanocarriers have been designed to accommodate varied usages, less studies have focused on the effects of nanomaterial physicochemical properties on immune responses, especially the immunity altered by nanocarrier materials alone. Conclusions are sometimes seemly inconsistent due to the complexities of nanomaterials and the immune system. An in-depth understanding of the nanocarrier-induced immune responses is essential for clinical applications. In this review, we summarize recent studies of the immune responses influenced by nanomaterial physicochemical properties with an emphasis on the intrinsic features of nanomaterials that modulate the innate and adaptive immunities. We then provide our perspectives on the design of nanomaterials for immunomodulation.
ArticleNumber 114039
Author Cheng, Hao
Li, Hongjun
Deng, Junjie
Fan, Zhiyuan
Gu, Zhen
Wang, Jilong
Shi, Jiaqi
Lu, Mingqin
Author_xml – sequence: 1
  givenname: Junjie
  surname: Deng
  fullname: Deng, Junjie
  organization: Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
– sequence: 2
  givenname: Jilong
  surname: Wang
  fullname: Wang, Jilong
  organization: Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
– sequence: 3
  givenname: Jiaqi
  surname: Shi
  fullname: Shi, Jiaqi
  organization: College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
– sequence: 4
  givenname: Hongjun
  surname: Li
  fullname: Li, Hongjun
  organization: College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
– sequence: 5
  givenname: Mingqin
  surname: Lu
  fullname: Lu, Mingqin
  organization: Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
– sequence: 6
  givenname: Zhiyuan
  surname: Fan
  fullname: Fan, Zhiyuan
  organization: Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA
– sequence: 7
  givenname: Zhen
  surname: Gu
  fullname: Gu, Zhen
  email: guzhen@zju.edu.cn
  organization: College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
– sequence: 8
  givenname: Hao
  surname: Cheng
  fullname: Cheng, Hao
  email: hcheng@drexel.edu
  organization: Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34742825$$D View this record in MEDLINE/PubMed
BookMark eNp9kM1KAzEURoMo2qov4EJm6WZqkkkmE3AjxT8oulFwF9LkxqbMTGoyI_j2prS6dBECyfk-7j1TdNiHHhC6IHhGMKmv1zNtbZxRTMmMEIYreYAmpBG0bKhkh2iSIVkyLN9P0DSlNcaEihofo5OKCUYbyifo-VX7NkTffxTDCorN6jt5E8wKOm90W2xi2EAcPKQiuKLXfej0ANHrNhUuxMJ33Zjfgh1bPfjQn6Ejl__gfH-forf7u9f5Y7l4eXia3y5KU_F6KC2lGsuKc-u0w8I1S0xN09S60sRYYZesFoLVhOvagnTCNoxKQ1nlRCMZd9Uputr15gE_R0iD6nwy0La6hzAmRbnkhOTDM0p3qIkhpQhObaLvdPxWBKutR7VWW49q61HtPObQ5b5_XHZg_yK_4jJwswMgb_nlIapkPPQGrI9gBmWD_6__B09ChrI
CitedBy_id crossref_primary_10_1016_j_jddst_2023_105184
crossref_primary_10_3390_pharmaceutics15041064
crossref_primary_10_1016_j_apmt_2024_102278
crossref_primary_10_1002_ange_202209499
crossref_primary_10_1002_adhm_202304496
crossref_primary_10_3390_ijms24032008
crossref_primary_10_1021_acsabm_3c00843
crossref_primary_10_1002_adma_202209778
crossref_primary_10_1002_anie_202209499
crossref_primary_10_3389_fimmu_2022_852147
crossref_primary_10_3390_jfb14010044
crossref_primary_10_1039_D4CS00421C
crossref_primary_10_1016_j_colcom_2022_100684
crossref_primary_10_1016_j_jconrel_2022_04_005
crossref_primary_10_1016_j_nantod_2022_101694
crossref_primary_10_1016_j_plana_2023_100039
crossref_primary_10_1016_j_addr_2023_115122
crossref_primary_10_1007_s13346_023_01290_2
crossref_primary_10_1016_j_addr_2022_114592
crossref_primary_10_1016_j_jconrel_2023_05_022
crossref_primary_10_1186_s12951_023_01930_2
Cites_doi 10.1038/ni.1937
10.1002/adma.202006160
10.1016/j.addr.2019.04.008
10.1002/adma.201706780
10.1016/j.biomaterials.2010.05.027
10.1038/s41578-019-0110-7
10.1371/journal.pcbi.1001068
10.1002/adhm.201700466
10.1016/j.omtn.2017.10.010
10.1021/acsnano.6b00053
10.1038/ni0205-219c
10.1038/nm.3893
10.1039/C8BM00463C
10.1016/j.drudis.2014.08.015
10.1056/NEJMoa2035389
10.1002/adhm.201700815
10.1021/acsnano.5b05583
10.1007/s12668-019-00638-8
10.1088/1361-6528/ab055f
10.1016/j.biomaterials.2010.11.080
10.1021/acsnano.1c02391
10.1016/j.biomaterials.2007.08.015
10.1038/nmat5057
10.1021/nn504905q
10.1038/nature17300
10.1021/ja809086q
10.1038/nnano.2017.113
10.1016/j.biomaterials.2010.01.065
10.1021/nl0730155
10.1080/17435390.2018.1564079
10.1038/s41565-020-0648-y
10.3892/wasj.2020.46
10.1021/acsnano.0c00602
10.1126/scitranslmed.aaw9668
10.1002/adma.201805740
10.1038/nature15373
10.1016/j.jaci.2021.04.002
10.1016/j.copbio.2020.07.006
10.1038/nri3488
10.1007/978-1-4614-0653-2_17
10.1038/s41467-020-20886-7
10.1016/j.biomaterials.2019.119299
10.1016/j.ymthe.2017.03.013
10.1021/acsnano.6b02086
10.1016/j.jconrel.2021.01.013
10.1007/s11051-016-3595-7
10.1016/j.nantod.2014.02.004
10.1016/j.cell.2017.03.006
10.1016/j.biomaterials.2018.08.022
10.1103/PhysRevLett.107.098101
10.1016/j.immuni.2013.05.016
10.1038/s41467-017-01015-3
10.1021/acs.nanolett.8b01283
10.1038/nmat4822
10.1038/s41577-019-0165-0
10.1126/sciadv.aax7964
10.1038/s41565-020-0669-6
10.1016/j.envres.2014.11.006
10.1021/nn2000756
10.1016/j.jconrel.2016.06.040
10.1016/j.jconrel.2005.02.027
10.1002/adtp.202100062
10.1073/pnas.1011368107
10.1289/ehp.1002201
10.1021/acsami.9b09900
10.1007/s11095-006-0069-0
10.1038/nnano.2007.70
10.1038/ni.1923
10.1016/j.bpj.2015.06.042
10.1021/acsnano.9b09213
10.1016/j.addr.2017.05.011
10.2217/nnm-2018-0052
10.1016/j.jconrel.2015.11.021
10.1038/nbt.4047
10.2217/nnm-2019-0159
10.1016/j.nantod.2017.03.001
10.1016/j.biomaterials.2010.07.056
10.1186/s41232-016-0013-6
10.1038/nbt1332
10.1021/acs.nanolett.8b01101
10.1111/bph.12722
10.1021/acsami.7b00677
10.1038/nnano.2016.269
10.1021/acs.bioconjchem.9b00847
10.1021/acs.chemrev.5b00691
10.1021/ar300031y
10.1002/smll.201801451
10.1038/nature18300
10.1038/cr.2009.139
10.1073/pnas.1616400113
10.1186/s11671-017-1828-z
10.1016/j.biomaterials.2010.07.067
10.1126/science.aay3638
10.1021/acsnano.7b07797
10.1073/pnas.1422923112
10.1016/j.jconrel.2008.05.005
10.1016/j.celrep.2017.01.004
10.1021/acs.biomac.6b00027
10.1242/jcs.114.6.1061
10.1021/acsnano.9b01444
10.1039/C9NR08261A
10.1038/s41467-018-06869-9
10.1016/j.copbio.2020.09.004
10.1080/01926230600867743
10.1007/s11427-020-1725-0
10.1073/pnas.1106634108
10.1021/nn100561e
10.1002/eji.200940168
10.1021/acs.chemrev.5b00109
10.1002/adhm.201901223
10.1021/acs.nanolett.9b03483
10.1002/smll.201907609
10.1038/nbt.2434
10.1021/acsnano.8b01806
10.1021/acs.nanolett.8b01089
10.1016/j.smim.2017.08.013
10.1001/jama.2021.1967
10.1089/ars.2012.5149
10.1039/C9CS00011A
10.1021/acsnano.6b06451
10.1021/ja2108905
10.1080/1547691X.2019.1605553
10.1111/cea.13874
10.1146/annurev-bioeng-071811-150124
10.1002/adma.201503323
10.1126/sciadv.aba1474
10.1021/acsnano.8b00242
10.1016/j.vaccine.2010.09.077
10.1038/nnano.2017.170
10.1021/acsnano.6b06061
10.1038/nnano.2015.330
10.1016/j.biomaterials.2011.01.021
10.3389/fimmu.2019.01958
10.1021/la303449d
10.1016/j.biomaterials.2013.09.050
10.1016/j.biomaterials.2015.07.048
10.1021/nn505125f
10.1021/acsnano.7b00497
10.1038/s41467-018-05396-x
10.1002/smll.200902074
10.1080/1547691X.2019.1695985
10.1039/c1cc10357a
10.1016/j.addr.2009.03.010
10.1002/adma.201907692
10.1002/smll.201502273
10.1073/pnas.1010013108
10.1021/acsnano.8b04947
10.1038/s41565-018-0274-0
10.1016/j.biomaterials.2014.02.012
10.1073/pnas.1820276116
10.1016/j.biomaterials.2019.119432
10.1056/NEJMoa2034577
10.1182/blood-2014-06-585299
10.1021/acs.bioconjchem.7b00793
10.1016/j.jconrel.2019.02.025
10.1021/acs.nanolett.7b03734
10.1053/j.gastro.2021.03.014
ContentType Journal Article
Copyright 2021 Elsevier B.V.
Copyright © 2021 Elsevier B.V. All rights reserved.
Copyright_xml – notice: 2021 Elsevier B.V.
– notice: Copyright © 2021 Elsevier B.V. All rights reserved.
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
DOI 10.1016/j.addr.2021.114039
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
Pharmacy, Therapeutics, & Pharmacology
EISSN 1872-8294
EndPage 114039
ExternalDocumentID 10_1016_j_addr_2021_114039
34742825
S0169409X21004324
Genre Research Support, Non-U.S. Gov't
Journal Article
Review
GroupedDBID ---
--K
--M
.~1
0R~
1B1
1RT
1~.
1~5
23M
4.4
457
4G.
53G
5GY
5VS
7-5
71M
8P~
9JM
AABNK
AACTN
AAEDT
AAEDW
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AATCM
AAXUO
ABFNM
ABGSF
ABJNI
ABMAC
ABUDA
ABXDB
ABYKQ
ABZDS
ACDAQ
ACGFS
ACIUM
ACRLP
ADBBV
ADEZE
ADMUD
ADUVX
AEBSH
AEHWI
AEKER
AENEX
AFKWA
AFTJW
AFXIZ
AGHFR
AGRDE
AGUBO
AGYEJ
AHHHB
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
ALCLG
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
C45
CS3
DOVZS
EBS
EFJIC
EFLBG
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HMT
HVGLF
HX~
HZ~
IHE
J1W
KOM
M34
M41
MO0
N9A
O-L
O9-
OAUVE
OGGZJ
OVD
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
ROL
RPZ
SCC
SDF
SDG
SDP
SES
SEW
SPCBC
SPT
SSP
SSU
SSZ
T5K
TEORI
WUQ
Y6R
~G-
AAXKI
ADVLN
AFJKZ
AKRWK
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
ID FETCH-LOGICAL-c356t-d22a09355dfaf07f8b02c886a3a1cd7db46774615a6de9f7d8429c243f78945f3
IEDL.DBID .~1
ISSN 0169-409X
IngestDate Thu Oct 24 23:57:21 EDT 2024
Thu Sep 26 17:51:52 EDT 2024
Sat Sep 28 08:22:56 EDT 2024
Fri Feb 23 02:40:41 EST 2024
IsPeerReviewed true
IsScholarly true
Keywords Nanomaterials
Complement
Drug delivery
Immunotherapy
Immunoengineering
Language English
License Copyright © 2021 Elsevier B.V. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c356t-d22a09355dfaf07f8b02c886a3a1cd7db46774615a6de9f7d8429c243f78945f3
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
PMID 34742825
PQID 2595119515
PQPubID 23479
PageCount 1
ParticipantIDs proquest_miscellaneous_2595119515
crossref_primary_10_1016_j_addr_2021_114039
pubmed_primary_34742825
elsevier_sciencedirect_doi_10_1016_j_addr_2021_114039
PublicationCentury 2000
PublicationDate January 2022
2022-01-00
20220101
PublicationDateYYYYMMDD 2022-01-01
PublicationDate_xml – month: 01
  year: 2022
  text: January 2022
PublicationDecade 2020
PublicationPlace Netherlands
PublicationPlace_xml – name: Netherlands
PublicationTitle Advanced drug delivery reviews
PublicationTitleAlternate Adv Drug Deliv Rev
PublicationYear 2022
Publisher Elsevier B.V
Publisher_xml – name: Elsevier B.V
References Getts, Martin, McCarthy, Terry, Hunter, Yap, Getts, Pleiss, Luo, King, Shea, Miller (b0305) 2012; 30
Kranz, Diken, Haas, Kreiter, Loquai, Reuter, Meng, Fritz, Vascotto, Hefesha, Grunwitz, Vormehr, Husemann, Selmi, Kuhn, Buck, Derhovanessian, Rae, Attig, Diekmann, Jabulowsky, Heesch, Hassel, Langguth, Grabbe, Huber, Tureci, Sahin (b0540) 2016; 534
Kinaret, Scala, Federico, Sund, Greco (b0225) 2020; 16
Oh, Kim, Choi, Kim, Jeong, Cho, Hahn, Jang (b0245) 2010; 4
Yang, Jambhrunkar, Abbaraju, Yu, Zhang, Yu (b0605) 2017; 6
Albanese, Tang, Chan (b0175) 2012; 14
Visalakshan, MacGregor, Sasidharan, Ghazaryan, Mierczynska-Vasilev, Morsbach, Mailander, Landfester, Hayball, Vasilev (b0750) 2019; 11
Vivier, Malissen (b0030) 2005; 6
Le, Winkler (b0780) 2016; 116
Ilinskaya, Dobrovolskaia (b0160) 2014; 171
Park, Zhang, Saito, Gurczynski, Moore, Cummings, Anderson, Shea (b0720) 2019; 116
Moghimi, Simberg (b0640) 2017; 15
Schöttler, Becker, Winzen, Steinbach, Mohr, Landfester, Mailander, Wurm (b0715) 2016; 11
Muñoz-Planillo, Kuffa, Martínez-Colón, Smith, Rajendiran, Núñez (b0045) 2013; 38
Park, Lim, Lim, Kwon, Choi, Jeong, Choi, Cheon (b0230) 2011; 47
Chen, Wang, Griffin, Brenneman, Banda, Holers, Backos, Wu, Moghimi, Simberg (b0275) 2017; 12
Orecchioni, Bedognetti, Newman, Fuoco, Spada, Hendrickx, Marincola, Sgarrella, Rodrigues, Menard-Moyon, Cesareni, Kostarelos, Bianco, Delogu (b0065) 2017; 8
Shimabukuro, Cole, Su (b0110) 2021; 325
Reddy, van der Vlies, Simeoni, Angeli, Randolph, O'Neil, Lee, Swartz, Hubbell (b0185) 2007; 25
Yi, Shi, Gao (b0475) 2011; 107
Horiuchi, Tsukamoto (b0625) 2016; 36
Saha, Rahimi, Yazdani, Kim, Moyano, Hou, Das, Mout, Rezaee, Mahmoudi, Rottello (b0620) 2016; 10
Saito, Kuo, Pearson, Gohel, Cheung, King, Miller, Shea (b0725) 2019; 300
Aillon, Xie, El-Gendy, Berkland, Forrest (b0320) 2009; 61
Cheng, Zhang, Fan, Zhang, Liu, Hong, Guo, Cui, Song (b0235) 2019; 11
Zhang, Dong, Gao, Lin, Liu, Wang (b0795) 2019; 5
Fytianos, Chortarea, Rodriguez-Lorenzo, Blank, Garnier, Petri-Fink, Rothen-Rutishauser (b0500) 2017; 11
Swanson, Deng, Ting (b0040) 2019; 19
He, Hu, Yin, Tang, Yin (b0490) 2010; 31
Heinrich (b0390) 2015; 109
Martinon (b0255) 2010; 40
Boraschi, Italiani, Palomba, Decuzzi, Duschl, Fadeel, Moghimi (b0055) 2017; 34
Talamini, Violatto, Cai, Monopoli, Kantner, Krpetic, Perez-Potti, Cookman, Garry, Silveira, Boselli, Pelaz, Serchi, Cambier, Gutleb, Feliu, Yan, Salmona, Parak, Dawson, Bigini (b0180) 2017; 11
Xia, Wu, Wei, Du, Wan, Ma, An, Guo, Miao, Yue, Li, Cao, Su, Ma (b0455) 2018; 17
Merkel, Jones, Herlihy, Kersey, Shields, Napier, Luft, Wu, Zamboni, Wang, Bear, DeSimone (b0450) 2011; 108
Ding, Yao, Yin, Li, Huang, Wu, Wang, Guo, Wang, Wu (b0170) 2018; 14
Mittal, Siddiqui, Tran, Reddy, Malik (b0250) 2014; 20
Elci, Jiang, Yan, Kim, Saha, Moyano, Tonga, Jackson, Rotello, Vachet (b0530) 2016; 10
Behr (b0580) 1997; 51
Xiao, Li, Luo, Lee, Xiao, Gonik, Agarwal, Lam (b0485) 2011; 32
Moyano, Goldsmith, Solfiell, Landesman-Milo, Miranda, Peer, Rotello (b0745) 2012; 134
Cai, Dong, Liu, Zheng, Kaweeteerawat, Wang, Ji, Li (b0370) 2018; 9
Hong, Halman, Shah, Khisamutdinov, Dobrovolskaia, Afonin (b0405) 2018; 18
Wang, Cui, Zhao, Chen (b0165) 2020; 63
May, Machesky (b0385) 2001; 114
Sellaturay, Nasser, Islam, Gurugama, Ewan, Allergy (b0120) 2021; 51
Guo, Li, Ma, Fu, Dong, Guo (b0400) 2017; 9
Dunkelberger, Song (b0655) 2010; 20
Sunshine, Perica, Schneck, Green (b0025) 2014; 35
Loftus, Saeed, Davis, Dunlop (b0150) 2018; 18
Du, Jiang, Das, Zhou, Yu, Jin, Zheng (b0190) 2017; 12
Hasani-Sadrabadi, Majedi, Bensinger, Wu, Bouchard, Weiss, Moshaverinia (b0445) 2018; 30
Du, Wang, Liu, Yang, Sun, Sun, Li, Shen, Luo, Ye, Zhu, Yang, Wang (b0675) 2015; 69
Oh, Kim, Yoon, Jang (b0345) 2010; 6
Hu, Fang, Wang, Luk, Thamphiwatana, Dehaini, Nguyen, Angsantikul, Wen, Kroll, Carpenter, Ramesh, Qu, Patel, Zhu, Shi, Hofman, Chen, Gao, Zhang, Chien, Zhang (b0760) 2015; 526
Wang, Du, Yang, Shen, Li, Luo, Iqbal, Xu, Ye, Cao, Wang (b0670) 2018; 182
Zhang, Kim, Thauland, Li, Majedi, Ly, Gu, Butte, Rowat, Li (b0410) 2020; 66
Kuai, Ochyl, Bahjat, Schwendeman, Moon (b0425) 2017; 16
Spiller, Anfang, Spiller, Ng, Nakazawa, Daulton, Vunjak-Novakovic (b0220) 2014; 35
Krienke, Kolb, Diken, Streuber, Kirchhoff, Bukur, Akilli-Ozturk, Kranz, Berger, Petschenka, Diken, Kreiter, Yogev, Waisman, Kariko, Tureci, Sahin (b0020) 2021; 371
Chen, Yan, Müllner, Ping, Cui, Kempe, Cortez-Jugo, Caruso (b0360) 2016; 17
Rizzuto, Salvioni, Rotem, Colombo, Zanoni, Granucci, Prosperi (b0070) 2019; 14
Risma, Edwards, Hummell, Little, Norton, Stallings, Wood, Milner (b0115) 2021
Li, Yang, Thambi, Park, Lee (b0510) 2019; 217
Chen, Yang, Yuan, Jin, Bao, Qiu, Liu, Liu, Gooding, Chen, Liu, Bai, Liu, Jin (b0680) 2021; 13
Freitas, Freitas, Lucas, Lucas, Sousa, Sousa, Soares, Soares, Ribeiro, Ribeiro, Carvalho, Carvalho, Fernandes, Fernandes (b0265) 2020
Galea, Nel, Talekar, Liu, Ooi, Huynh, Hadjigol, Robson, Ting, Cole, Cochlin, Hitchcock, Zeng, Yekollu, Boks, Goh, Roberts, Rossjohn, Reid, Boyd, Malaviya, Shealy, Baker, Madakamutil, Kitching, O’Sullivan, Thomas (b0435) 2019; 18
Qi, Liu, Matiski, Rodriguez Del Villar, Yip, Zhang, Sokalingam, Jiang, Liu, Yan, Chang (b0395) 2020; 14
Min, Roche, Tian, Eblan, McKinnon, Caster, Chai, Herring, Zhang, Zhang, DeSimone, Tepper, Vincent, Serody, Wang (b0710) 2017; 12
Kim, Oh, Jeong, Hong, Cho, Hahn, Jang (b0260) 2011; 32
Hu, Sun, Qian, Wang, Bomba, Gu (b0765) 2015; 27
Zhang, Sun, Liu, Jiang (b0085) 2016; 244
Cheung, Zhang, Koshy, Mooney (b0295) 2018; 36
Cesta (b0535) 2006; 34
Yan, Chen, Huang (b0550) 2008; 130
Yi, Allen, Liu, Ouyang, Li, Augsornworawat, Thorp, Scott (b0365) 2016; 10
Quach, Kong, Kah (b0635) 2018; 29
Cai, Chen (b0615) 2019; 31
Taylor, Husain, Gartner, Mayor, Vale (b0290) 2017; 169
Fromen, Robbins, Shen, Kai, Ting, DeSimone (b0570) 2015; 112
Müllner, Dodds, Nguyen, Senyschyn, Porter, Boyd, Caruso (b0415) 2015; 9
Schudel, Francis, Thomas (b0440) 2019; 4
Cho, Duffin, Poland, Howie, MacNee, Bradley, Megson, Donaldson (b0060) 2010; 118
Wang, Jönsson (b0800) 2019; 10
Nangia, Sureshkumar (b0480) 2012; 28
Mou, Xing, Ren, Cui, Zhang, Yu, Urba, Hu, Hu (b0575) 2017; 12
Vincent, Karabin, Allen, Bobbala, Frey, Yi, Yang, Scott (b0775) 2021; 4
Kelly, Murray, Leffler, Getts, Bledsoe, Smithson, First, Morris, Boyne, Elhofy (b0315) 2021
Szebeni, Bedőcs, Rozsnyay, Weiszhár, Urbanics, Rosivall, Cohen, Garbuzenko, Báthori, Tóth, Bünger, Barenholz (b0520) 2012; 8
Roach, Stefaniak, Roberts (b0155) 2019; 16
van Pomeren, Peijnenburg, Vlieg, van Noort, Vijver (b0340) 2019; 13
Kolishetti, Dhar, Valencia, Lin, Karnik, Lippard, Langer, Farokhzad (b0200) 2010; 107
Kedmi, Ben-Arie, Peer (b0565) 2010; 31
Donahue, Acar, Wilhelm (b0075) 2019; 143
Shen, Dai, Fei, Chai, Hao, Fan, Dong, Zhu, Xu, Ma, Han, Xu, Peng, Liu, Wang (b0770) 2021; 15
Richter, Åkerblom (b0690) 1983; 70
Cheng, Wei, Farbiak, Johnson, Dilliard, Siegwart (b0525) 2020; 15
Frey, Bobbala, Karabin, Scott (b0350) 2018; 13
Zhu, Nie, Meng, Xia, Nel, Zhao (b0325) 2013; 46
Wang, Gan, Iqbal, Jiang, Yuan, Wang (b0515) 2018; 6
Herant, Lee, Dembo, Heinrich, McCulloch (b0380) 2011; 7
Baden, El Sahly, Essink, Kotloff, Frey, Novak, Diemert, Spector, Rouphael, Creech, McGettigan, Khetan, Segall, Solis, Brosz, Fierro, Schwartz, Neuzil, Corey, Gilbert, Janes, Follmann, Marovich, Mascola, Polakowski, Ledgerwood, Graham, Bennett, Pajon, Knightly, Leav, Deng, Zhou, Han, Ivarsson, Miller, Zaks, Group (b0105) 2021; 384
Saito, Kuo, Kramer, Gohel, Giles, Moore, Miller, Shea (b0730) 2019; 222
Irvine, Hanson, Rakhra, Tokatlian (b0015) 2015; 115
Mukherjee, Kostarelos, Fadeel (b0240) 2018; 7
Wang, Zhou, Bian, Wang, Chai, Guo, Wang, Zhu, Peng, Yan, Li, Fu, Zhu (b0095) 2020; 15
Cifuentes-Rius, Boase, Font, Coronas, Ramos-Perez, Thurecht, Borrós (b0420) 2017; 9
Liu, Wang, Liu, Kumar, Gochman, Ji, Liao, Chang, Situ, Lu, Jiang, Mei, Meng, Xia, Nei (b0735) 2019; 13
Zhou, Mu, Gao, Liu, Xing, Gao, Zhang, Qu, Chen, Liu, Zhang, Yan (b0145) 2008; 8
Safari, Kelley, Saito, Kaczorowski, Carethers, Shea, Eniola-Adefeso (b0375) 2020; 6
Huang, Hsiao, Lin, Wang, Huang, Chuang (b0270) 2015; 136
Kanchan, Panda (b0300) 2007; 28
Qi, Zhou, Tang, Lee, Fan, Kim, Staub, Zhou, Mei, Han, Pochan, Chen, Hu, Li (b0205) 2018; 9
Wraith (b0010) 2016; 530
Hirosue, Kourtis, van der Vlies, Hubbell, Swartz (b0585) 2010; 28
Srijampa, Buddhisa, Ngernpimai, Leelayuwat, Proungvitaya, Chompoosor, Tippayawat (b0545) 2020; 31
Pham, Thomas, Beiser, Mitchell, Huang, Senpan, Hu, Gordon, Baker, Pan, Lanza, Hourcade (b0595) 2014; 10
Hickey, Vicente, Howard, Mao, Schneck (b0285) 2017; 17
Ricklin, Hajishengallis, Yang, Lambris (b0650) 2010; 11
Zhou, Fan, Li, Deng, Arhontoulis, Li, Bowne, Chen (b0810) 2018; 12
Kettler, Giannakou, de Jong, Hendriks, Krystek (b0210) 2016; 18
Ball, Hajj, Vizelman, Bajaj, Whitehead (b0130) 2018; 18
Wang, Chen, Hang, Yu, Liu, He, Xiao, Yang, Yang, Liu, Tao, Wu, Xie (b0355) 2018; 13
Moyano, Liu, Peer, Rotello (b0695) 2016; 12
Smith, Simon, Baker (b0090) 2013; 13
Kwon, Standley, Goh, Frechet (b0495) 2005; 105
Palomba, Palange, Rizzuti, Ferreira, Cervadoro, Barbato, Canale, Decuzzi (b0470) 2018; 12
Cullis, Hope (b0125) 2017; 25
Yang, Zhou, Song, Chen (b0330) 2019; 48
Hui, Wibowo, Liu, Ran, Wang, Seth, Middelberg, Zhao (b0460) 2018; 12
Zhao, Bi, Qi, Guo, Yue, Wang, Han (b0600) 2019; 30
Sosale, Rouhiparkouhi, Bradshaw, Dimova, Lipowsky, Discher (b0465) 2015; 125
Chen, Li, Yin, Cai, Huang, Chen, Dong, Zhang (b0560) 2010; 31
Chu, Gao, Wang (b0790) 2015; 9
Lunov, Syrovets, Loos, Beil, Delacher, Tron, Nienhaus, Musyanovych, Mailänder, Landfester, Simmet (b0505) 2011; 5
Wang, Huang, Yu, Zang, Ye, Zhu (b0645) 2020; 17
Vincent, Bobbala, Karabin, Frey, Liu, Navidzadeh, Stack, Scott (b0785) 2021; 12
Tsugita, Morimoto, Tashiro, Kinoshita, Nakayama (b0050) 2017; 18
Bertholon, Vauthier, Labarre (b0665) 2006; 23
Polack, Thomas, Kitchin, Absalon, Gurtman, Lockhart, Perez, Perez Marc, Moreira, Zerbini, Bailey, Swanson, Roychoudhury, Koury, Li, Kalina, Cooper, Frenck, Hammitt, Tureci, Nell, Schaefer, Unal, Tresnan, Mather, Dormitzer, Sahin, Jansen, Gruber, Group (b0100) 2020; 383
Fan, Zhu, Zhu, Wu, Li, Che
Donahue (10.1016/j.addr.2021.114039_b0075) 2019; 143
Ricklin (10.1016/j.addr.2021.114039_b0650) 2010; 11
Du (10.1016/j.addr.2021.114039_b0675) 2015; 69
Vivier (10.1016/j.addr.2021.114039_b0030) 2005; 6
Quach (10.1016/j.addr.2021.114039_b0635) 2018; 29
Shimabukuro (10.1016/j.addr.2021.114039_b0110) 2021; 325
Chen (10.1016/j.addr.2021.114039_b0360) 2016; 17
Hu (10.1016/j.addr.2021.114039_b0755) 2011; 108
Aillon (10.1016/j.addr.2021.114039_b0320) 2009; 61
He (10.1016/j.addr.2021.114039_b0490) 2010; 31
Cesta (10.1016/j.addr.2021.114039_b0535) 2006; 34
Srijampa (10.1016/j.addr.2021.114039_b0545) 2020; 31
Zhu (10.1016/j.addr.2021.114039_b0325) 2013; 46
Dunkelberger (10.1016/j.addr.2021.114039_b0655) 2010; 20
Taylor (10.1016/j.addr.2021.114039_b0290) 2017; 169
Yan (10.1016/j.addr.2021.114039_b0550) 2008; 130
Chen (10.1016/j.addr.2021.114039_b0680) 2021; 13
Pham (10.1016/j.addr.2021.114039_b0595) 2014; 10
Kanchan (10.1016/j.addr.2021.114039_b0300) 2007; 28
Cheng (10.1016/j.addr.2021.114039_b0525) 2020; 15
Wang (10.1016/j.addr.2021.114039_b0355) 2018; 13
Szebeni (10.1016/j.addr.2021.114039_b0520) 2012; 8
Li (10.1016/j.addr.2021.114039_b0740) 2021; 33
Saha (10.1016/j.addr.2021.114039_b0620) 2016; 10
Lunov (10.1016/j.addr.2021.114039_b0505) 2011; 5
Herant (10.1016/j.addr.2021.114039_b0380) 2011; 7
Wang (10.1016/j.addr.2021.114039_b0670) 2018; 182
Zhou (10.1016/j.addr.2021.114039_b0810) 2018; 12
van Pomeren (10.1016/j.addr.2021.114039_b0340) 2019; 13
Orecchioni (10.1016/j.addr.2021.114039_b0065) 2017; 8
Zhang (10.1016/j.addr.2021.114039_b0410) 2020; 66
Schöttler (10.1016/j.addr.2021.114039_b0715) 2016; 11
Hong (10.1016/j.addr.2021.114039_b0405) 2018; 18
Le (10.1016/j.addr.2021.114039_b0780) 2016; 116
Frey (10.1016/j.addr.2021.114039_b0350) 2018; 13
Boraschi (10.1016/j.addr.2021.114039_b0055) 2017; 34
Xia (10.1016/j.addr.2021.114039_b0455) 2018; 17
Wang (10.1016/j.addr.2021.114039_b0095) 2020; 15
Oh (10.1016/j.addr.2021.114039_b0245) 2010; 4
Rizzuto (10.1016/j.addr.2021.114039_b0070) 2019; 14
Krienke (10.1016/j.addr.2021.114039_b0020) 2021; 371
Yi (10.1016/j.addr.2021.114039_b0475) 2011; 107
Fromen (10.1016/j.addr.2021.114039_b0570) 2015; 112
Richter (10.1016/j.addr.2021.114039_b0690) 1983; 70
Risma (10.1016/j.addr.2021.114039_b0115) 2021
Polack (10.1016/j.addr.2021.114039_b0100) 2020; 383
Galea (10.1016/j.addr.2021.114039_b0435) 2019; 18
Cho (10.1016/j.addr.2021.114039_b0060) 2010; 118
Cheng (10.1016/j.addr.2021.114039_b0235) 2019; 11
Merkel (10.1016/j.addr.2021.114039_b0450) 2011; 108
Muñoz-Planillo (10.1016/j.addr.2021.114039_b0045) 2013; 38
Xiao (10.1016/j.addr.2021.114039_b0485) 2011; 32
Saito (10.1016/j.addr.2021.114039_b0730) 2019; 222
Liu (10.1016/j.addr.2021.114039_b0735) 2019; 13
Mangraviti (10.1016/j.addr.2021.114039_b0135) 2015; 9
Kwon (10.1016/j.addr.2021.114039_b0495) 2005; 105
Yang (10.1016/j.addr.2021.114039_b0330) 2019; 48
Horiuchi (10.1016/j.addr.2021.114039_b0625) 2016; 36
Visalakshan (10.1016/j.addr.2021.114039_b0750) 2019; 11
Correa (10.1016/j.addr.2021.114039_b0610) 2020; 14
Vincent (10.1016/j.addr.2021.114039_b0785) 2021; 12
Yang (10.1016/j.addr.2021.114039_b0685) 2014; 9
Biswas (10.1016/j.addr.2021.114039_b0215) 2010; 11
Safari (10.1016/j.addr.2021.114039_b0375) 2020; 6
Yang (10.1016/j.addr.2021.114039_b0605) 2017; 6
Reddy (10.1016/j.addr.2021.114039_b0185) 2007; 25
Zhang (10.1016/j.addr.2021.114039_b0805) 2020; 32
Kelly (10.1016/j.addr.2021.114039_b0315) 2021
Son (10.1016/j.addr.2021.114039_b0430) 2020; 20
Hirosue (10.1016/j.addr.2021.114039_b0585) 2010; 28
Hickey (10.1016/j.addr.2021.114039_b0285) 2017; 17
Tsugita (10.1016/j.addr.2021.114039_b0050) 2017; 18
Kim (10.1016/j.addr.2021.114039_b0260) 2011; 32
Li (10.1016/j.addr.2021.114039_b0280) 2021; 331
Heinrich (10.1016/j.addr.2021.114039_b0390) 2015; 109
Sosale (10.1016/j.addr.2021.114039_b0465) 2015; 125
Zhang (10.1016/j.addr.2021.114039_b0085) 2016; 244
Kinaret (10.1016/j.addr.2021.114039_b0225) 2020; 16
Freitas (10.1016/j.addr.2021.114039_b0265) 2020
Dash (10.1016/j.addr.2021.114039_b0590) 2010; 31
Yi (10.1016/j.addr.2021.114039_b0365) 2016; 10
Hui (10.1016/j.addr.2021.114039_b0460) 2018; 12
Wang (10.1016/j.addr.2021.114039_b0165) 2020; 63
Nangia (10.1016/j.addr.2021.114039_b0480) 2012; 28
Kang (10.1016/j.addr.2021.114039_b0140) 2020; 9
Milling (10.1016/j.addr.2021.114039_b0005) 2017; 114
Huang (10.1016/j.addr.2021.114039_b0270) 2015; 136
Hu (10.1016/j.addr.2021.114039_b0760) 2015; 526
Chen (10.1016/j.addr.2021.114039_b0560) 2010; 31
Sellaturay (10.1016/j.addr.2021.114039_b0120) 2021; 51
Wang (10.1016/j.addr.2021.114039_b0645) 2020; 17
Shen (10.1016/j.addr.2021.114039_b0770) 2021; 15
Cai (10.1016/j.addr.2021.114039_b0370) 2018; 9
Moyano (10.1016/j.addr.2021.114039_b0695) 2016; 12
Falagan-Lotsch (10.1016/j.addr.2021.114039_b0705) 2016; 113
Smith (10.1016/j.addr.2021.114039_b0090) 2013; 13
Zhou (10.1016/j.addr.2021.114039_b0145) 2008; 8
Ilinskaya (10.1016/j.addr.2021.114039_b0160) 2014; 171
Bertholon (10.1016/j.addr.2021.114039_b0665) 2006; 23
Irvine (10.1016/j.addr.2021.114039_b0015) 2015; 115
Sunshine (10.1016/j.addr.2021.114039_b0025) 2014; 35
Albanese (10.1016/j.addr.2021.114039_b0175) 2012; 14
Elci (10.1016/j.addr.2021.114039_b0530) 2016; 10
Cifuentes-Rius (10.1016/j.addr.2021.114039_b0420) 2017; 9
Wraith (10.1016/j.addr.2021.114039_b0010) 2016; 530
Mittal (10.1016/j.addr.2021.114039_b0250) 2014; 20
Oh (10.1016/j.addr.2021.114039_b0345) 2010; 6
Fytianos (10.1016/j.addr.2021.114039_b0500) 2017; 11
Chu (10.1016/j.addr.2021.114039_b0790) 2015; 9
Du (10.1016/j.addr.2021.114039_b0190) 2017; 12
Tavano (10.1016/j.addr.2021.114039_b0630) 2018; 12
Ding (10.1016/j.addr.2021.114039_b0170) 2018; 14
Müllner (10.1016/j.addr.2021.114039_b0415) 2015; 9
Cai (10.1016/j.addr.2021.114039_b0615) 2019; 31
Li (10.1016/j.addr.2021.114039_b0510) 2019; 217
Qi (10.1016/j.addr.2021.114039_b0205) 2018; 9
Schudel (10.1016/j.addr.2021.114039_b0440) 2019; 4
Zhang (10.1016/j.addr.2021.114039_b0795) 2019; 5
Roach (10.1016/j.addr.2021.114039_b0155) 2019; 16
Hu (10.1016/j.addr.2021.114039_b0765) 2015; 27
Miller (10.1016/j.addr.2021.114039_b0310) 2012; 724
Palomba (10.1016/j.addr.2021.114039_b0470) 2018; 12
Kettler (10.1016/j.addr.2021.114039_b0210) 2016; 18
Martinon (10.1016/j.addr.2021.114039_b0255) 2010; 40
Guo (10.1016/j.addr.2021.114039_b0400) 2017; 9
Kuai (10.1016/j.addr.2021.114039_b0425) 2017; 16
Wang (10.1016/j.addr.2021.114039_b0800) 2019; 10
Chen (10.1016/j.addr.2021.114039_b0275) 2017; 12
Spiller (10.1016/j.addr.2021.114039_b0220) 2014; 35
Baden (10.1016/j.addr.2021.114039_b0105) 2021; 384
Srijampa (10.1016/j.addr.2021.114039_b0555) 2019; 9
Loftus (10.1016/j.addr.2021.114039_b0150) 2018; 18
Saito (10.1016/j.addr.2021.114039_b0725) 2019; 300
Prencipe (10.1016/j.addr.2021.114039_b0080) 2009; 131
Mou (10.1016/j.addr.2021.114039_b0575) 2017; 12
Moghimi (10.1016/j.addr.2021.114039_b0640) 2017; 15
Cheung (10.1016/j.addr.2021.114039_b0295) 2018; 36
Behr (10.1016/j.addr.2021.114039_b0580) 1997; 51
Min (10.1016/j.addr.2021.114039_b0710) 2017; 12
Fan (10.1016/j.addr.2021.114039_b0195) 2020; 66
Swanson (10.1016/j.addr.2021.114039_b0040) 2019; 19
Kedmi (10.1016/j.addr.2021.114039_b0565) 2010; 31
Park (10.1016/j.addr.2021.114039_b0720) 2019; 116
Geng (10.1016/j.addr.2021.114039_b0335) 2007; 2
Kolishetti (10.1016/j.addr.2021.114039_b0200) 2010; 107
Ball (10.1016/j.addr.2021.114039_b0130) 2018; 18
Vincent (10.1016/j.addr.2021.114039_b0775) 2021; 4
May (10.1016/j.addr.2021.114039_b0385) 2001; 114
Wang (10.1016/j.addr.2021.114039_b0515) 2018; 6
Moyano (10.1016/j.addr.2021.114039_b0745) 2012; 134
Getts (10.1016/j.addr.2021.114039_b0305) 2012; 30
Verhoef (10.1016/j.addr.2021.114039_b0700) 2014; 19
Mukherjee (10.1016/j.addr.2021.114039_b0240) 2018; 7
Hasani-Sadrabadi (10.1016/j.addr.2021.114039_b0445) 2018; 30
Qi (10.1016/j.addr.2021.114039_b0395) 2020; 14
Cullis (10.1016/j.addr.2021.114039_b0125) 2017; 25
Park (10.1016/j.addr.2021.114039_b0230) 2011; 47
Guo (10.1016/j.addr.2021.114039_b0035) 2015; 21
Zhao (10.1016/j.addr.2021.114039_b0600) 2019; 30
Wibroe (10.1016/j.addr.2021.114039_b0660) 2016; 221
Talamini (10.1016/j.addr.2021.114039_b0180) 2017; 11
Kranz (10.1016/j.addr.2021.114039_b0540) 2016; 534
References_xml – volume: 9
  start-page: 580
  year: 2019
  end-page: 586
  ident: b0555
  article-title: Effects of gold nanoparticles with different surface charges on cellular internalization and cytokine responses in monocytes
  publication-title: BioNanoScience
  contributor:
    fullname: Tippayawat
– volume: 4
  start-page: 2100062
  year: 2021
  ident: b0775
  article-title: The combination of morphology and surface chemistry defines the immunological identity of nanocarriers in human blood
  publication-title: Adv. Ther.
  contributor:
    fullname: Scott
– volume: 20
  start-page: 1499
  year: 2020
  end-page: 1509
  ident: b0430
  article-title: Sugar-nanocapsules imprinted with microbial molecular patterns for mRNA vaccination
  publication-title: Nano Lett.
  contributor:
    fullname: Moon
– volume: 12
  start-page: 2846
  year: 2018
  end-page: 2857
  ident: b0460
  article-title: Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting
  publication-title: ACS Nano
  contributor:
    fullname: Zhao
– volume: 13
  start-page: 1795
  year: 2018
  end-page: 1811
  ident: b0350
  article-title: Influences of nanocarrier morphology on therapeutic immunomodulation
  publication-title: Nanomedicine (London U. K.)
  contributor:
    fullname: Scott
– volume: 36
  start-page: 160
  year: 2018
  end-page: 169
  ident: b0295
  article-title: Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells
  publication-title: Nat. Biotechnol.
  contributor:
    fullname: Mooney
– volume: 526
  start-page: 118
  year: 2015
  end-page: 121
  ident: b0760
  article-title: Nanoparticle biointerfacing by platelet membrane cloaking
  publication-title: Nature
  contributor:
    fullname: Zhang
– volume: 13
  start-page: 592
  year: 2013
  end-page: 605
  ident: b0090
  article-title: Applications of nanotechnology for immunology
  publication-title: Nat. Rev. Immunol.
  contributor:
    fullname: Baker
– volume: 12
  start-page: 1096
  year: 2017
  end-page: 1102
  ident: b0190
  article-title: Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Zheng
– volume: 217
  start-page: 119299
  year: 2019
  ident: b0510
  article-title: Charge-convertible polymers for improved tumor targeting and enhanced therapy
  publication-title: Biomaterials
  contributor:
    fullname: Lee
– volume: 34
  start-page: 33
  year: 2017
  end-page: 51
  ident: b0055
  article-title: Nanoparticles and innate immunity: new perspectives on host defence
  publication-title: Semin. Immunol.
  contributor:
    fullname: Moghimi
– volume: 31
  start-page: 6867
  year: 2010
  end-page: 6875
  ident: b0565
  article-title: The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation
  publication-title: Biomaterials
  contributor:
    fullname: Peer
– volume: 14
  start-page: 2224
  year: 2020
  end-page: 2237
  ident: b0610
  article-title: Tuning nanoparticle interactions with ovarian cancer through layer-by-layer modification of surface chemistry
  publication-title: ACS Nano
  contributor:
    fullname: Hammond
– volume: 12
  start-page: 387
  year: 2017
  end-page: 393
  ident: b0275
  article-title: Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Simberg
– volume: 18
  year: 2019
  ident: b0435
  article-title: PD-L1–and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease
  publication-title: JCI insight
  contributor:
    fullname: Thomas
– volume: 38
  start-page: 1142
  year: 2013
  end-page: 1153
  ident: b0045
  article-title: K
  publication-title: Immunity
  contributor:
    fullname: Núñez
– volume: 4
  start-page: 415
  year: 2019
  end-page: 428
  ident: b0440
  article-title: Material design for lymph node drug delivery
  publication-title: Nat. Rev. Mater.
  contributor:
    fullname: Thomas
– volume: 118
  start-page: 1699
  year: 2010
  end-page: 1706
  ident: b0060
  article-title: Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing
  publication-title: Environ. Health Perspect.
  contributor:
    fullname: Donaldson
– volume: 143
  start-page: 68
  year: 2019
  end-page: 96
  ident: b0075
  article-title: Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
  publication-title: Adv. Drug Delivery Rev.
  contributor:
    fullname: Wilhelm
– volume: 4
  start-page: 5301
  year: 2010
  end-page: 5313
  ident: b0245
  article-title: Cellular uptake, cytotoxicity, and innate immune response of silica-titania hollow nanoparticles based on size and surface functionality
  publication-title: ACS Nano
  contributor:
    fullname: Jang
– volume: 9
  start-page: 1294
  year: 2015
  end-page: 1304
  ident: b0415
  article-title: Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo
  publication-title: ACS Nano
  contributor:
    fullname: Caruso
– volume: 16
  start-page: 87
  year: 2019
  end-page: 124
  ident: b0155
  article-title: Metal nanomaterials: Immune effects and implications of physicochemical properties on sensitization, elicitation, and exacerbation of allergic disease
  publication-title: J. Immunotoxicol.
  contributor:
    fullname: Roberts
– volume: 113
  start-page: 13318
  year: 2016
  end-page: 13323
  ident: b0705
  article-title: One low-dose exposure of gold nanoparticles induces long-term changes in human cells
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Murphy
– volume: 7
  start-page: 1700815
  year: 2018
  ident: b0240
  article-title: Cytokine profiling of primary human macrophages exposed to endotoxin-free graphene oxide: size-independent NLRP3 inflammasome activation
  publication-title: Adv. Healthcare Mater.
  contributor:
    fullname: Fadeel
– volume: 31
  start-page: 8172
  year: 2010
  end-page: 8180
  ident: b0560
  article-title: The promotion of type 1 T helper cell responses to cationic polymers in vivo
  publication-title: Biomaterials
  contributor:
    fullname: Zhang
– volume: 134
  start-page: 3965
  year: 2012
  end-page: 3967
  ident: b0745
  article-title: Nanoparticle hydrophobicity dictates immune response
  publication-title: J. Am. Chem. Soc.
  contributor:
    fullname: Rotello
– volume: 300
  start-page: 185
  year: 2019
  end-page: 196
  ident: b0725
  article-title: Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation
  publication-title: J. Controlled Release
  contributor:
    fullname: Shea
– volume: 30
  start-page: 1217
  year: 2012
  end-page: 1224
  ident: b0305
  article-title: Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
  publication-title: Nat. Biotechnol.
  contributor:
    fullname: Miller
– volume: 6
  start-page: 872
  year: 2010
  end-page: 879
  ident: b0345
  article-title: Shape-dependent cytotoxicity and proinflammatory response of poly(3,4-ethylenedioxythiophene) nanomaterials
  publication-title: Small
  contributor:
    fullname: Jang
– volume: 14
  start-page: 1801451
  year: 2018
  ident: b0170
  article-title: Size, shape, and protein corona determine cellular uptake and removal mechanisms of gold nanoparticles
  publication-title: Small
  contributor:
    fullname: Wu
– volume: 11
  start-page: 5519
  year: 2017
  end-page: 5529
  ident: b0180
  article-title: Influence of size and shape on the anatomical distribution of endotoxin-free gold nanoparticles
  publication-title: ACS Nano
  contributor:
    fullname: Bigini
– volume: 19
  start-page: 1945
  year: 2014
  end-page: 1952
  ident: b0700
  article-title: Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics
  publication-title: Drug Discovery Today
  contributor:
    fullname: Schellekens
– year: 2020
  ident: b0265
  article-title: Small-size silver nanoparticles stimulate neutrophil oxidative burst through an increase of intracellular calcium levels
  publication-title: World Acad. Sci. J.
  contributor:
    fullname: Fernandes
– volume: 18
  start-page: 3814
  year: 2018
  end-page: 3822
  ident: b0130
  article-title: Lipid nanoparticle formulations for enhanced co-delivery of siRNA and mRNA
  publication-title: Nano Lett.
  contributor:
    fullname: Whitehead
– volume: 29
  start-page: 976
  year: 2018
  end-page: 981
  ident: b0635
  article-title: Complement activation by PEGylated gold nanoparticles
  publication-title: Bioconjug. Chem.
  contributor:
    fullname: Kah
– volume: 108
  start-page: 10980
  year: 2011
  end-page: 10985
  ident: b0755
  article-title: Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Zhang
– volume: 130
  start-page: 22
  year: 2008
  end-page: 28
  ident: b0550
  article-title: Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine
  publication-title: J. Controlled Release
  contributor:
    fullname: Huang
– volume: 18
  start-page: 3282
  year: 2018
  end-page: 3289
  ident: b0150
  article-title: Activation of human natural killer cells by graphene oxide-templated antibody nanoclusters
  publication-title: Nano Lett.
  contributor:
    fullname: Dunlop
– volume: 14
  start-page: 2379
  year: 2019
  end-page: 2390
  ident: b0070
  article-title: Are nanotechnological approaches the future of treating inflammatory diseases?
  publication-title: Nanomedicine (London, U. K.)
  contributor:
    fullname: Prosperi
– volume: 221
  start-page: 1
  year: 2016
  end-page: 8
  ident: b0660
  article-title: An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil(R), Caelyx(R), DOXOrubicin, and SinaDoxosome
  publication-title: J. Controlled Release
  contributor:
    fullname: Moghimi
– volume: 331
  start-page: 164
  year: 2021
  end-page: 175
  ident: b0280
  article-title: PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance
  publication-title: J. Controlled Release
  contributor:
    fullname: Cheng
– volume: 13
  start-page: 4778
  year: 2019
  end-page: 4794
  ident: b0735
  article-title: Use of polymeric nanoparticle platform targeting the liver to induce treg-mediated antigen-specific immune tolerance in a pulmonary allergen sensitization model
  publication-title: ACS Nano
  contributor:
    fullname: Nei
– volume: 34
  start-page: 455
  year: 2006
  end-page: 465
  ident: b0535
  article-title: Normal structure, function, and histology of the spleen
  publication-title: Toxicol. Pathol.
  contributor:
    fullname: Cesta
– volume: 31
  start-page: 3657
  year: 2010
  end-page: 3666
  ident: b0490
  article-title: Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
  publication-title: Biomaterials
  contributor:
    fullname: Yin
– volume: 9
  start-page: 1236
  year: 2015
  end-page: 1249
  ident: b0135
  article-title: Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo
  publication-title: ACS Nano
  contributor:
    fullname: Green
– volume: 16
  start-page: 1907609
  year: 2020
  ident: b0225
  article-title: Carbon nanomaterials promote M1/M2 macrophage activation
  publication-title: Small
  contributor:
    fullname: Greco
– volume: 20
  start-page: 1126
  year: 2014
  end-page: 1167
  ident: b0250
  article-title: Reactive oxygen species in inflammation and tissue injury
  publication-title: Antioxid. Redox Signaling
  contributor:
    fullname: Malik
– volume: 5
  start-page: 1657
  year: 2011
  end-page: 1669
  ident: b0505
  article-title: Differential uptake of functionalized polystyrene nanoparticles by human macrophages and a monocytic cell line
  publication-title: ACS Nano
  contributor:
    fullname: Simmet
– volume: 112
  start-page: 488
  year: 2015
  end-page: 493
  ident: b0570
  article-title: Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: DeSimone
– volume: 9
  start-page: 1
  year: 2018
  end-page: 10
  ident: b0205
  article-title: Block copolymer crystalsomes with an ultrathin shell to extend blood circulation time
  publication-title: Nat. Commun.
  contributor:
    fullname: Li
– volume: 7
  start-page: e1001068
  year: 2011
  ident: b0380
  article-title: Protrusive push versus enveloping embrace: computational model of phagocytosis predicts key regulatory role of cytoskeletal membrane anchors
  publication-title: PLoS Comput. Biol.
  contributor:
    fullname: McCulloch
– volume: 11
  start-page: 22849
  year: 2019
  end-page: 22859
  ident: b0235
  article-title: The vacuolization of macrophages induced by large amounts of inorganic nanoparticle uptake to enhance the immune response
  publication-title: Nanoscale
  contributor:
    fullname: Song
– volume: 18
  start-page: 1298
  year: 2017
  end-page: 1311
  ident: b0050
  article-title: SR-B1 is a silica receptor that mediates canonical inflammasome activation
  publication-title: Cell Rep.
  contributor:
    fullname: Nakayama
– volume: 534
  start-page: 396
  year: 2016
  end-page: 401
  ident: b0540
  article-title: Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
  publication-title: Nature
  contributor:
    fullname: Sahin
– volume: 6
  start-page: 219
  year: 2005
  ident: b0030
  article-title: Innate and adaptive immunity: specificities and signaling hierarchies revisited
  publication-title: Nat. Immunol.
  contributor:
    fullname: Malissen
– volume: 11
  start-page: 27615
  year: 2019
  end-page: 27623
  ident: b0750
  article-title: Biomaterial surface hydrophobicity-mediated serum protein adsorption and immune responses
  publication-title: ACS Appl. Mater. Interfaces
  contributor:
    fullname: Vasilev
– volume: 31
  start-page: 8188
  year: 2010
  end-page: 8197
  ident: b0590
  article-title: The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility
  publication-title: Biomaterials
  contributor:
    fullname: Pandit
– volume: 9
  start-page: 1901223
  year: 2020
  ident: b0140
  article-title: Size-dependent EPR effect of polymeric nanoparticles on tumor targeting
  publication-title: Adv. Healthcare Mater.
  contributor:
    fullname: Choi
– volume: 5
  year: 2019
  ident: b0795
  article-title: Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke
  publication-title: Sci. Adv.
  contributor:
    fullname: Wang
– volume: 16
  start-page: 489
  year: 2017
  end-page: 496
  ident: b0425
  article-title: Designer vaccine nanodiscs for personalized cancer immunotherapy
  publication-title: Nat. Mater.
  contributor:
    fullname: Moon
– volume: 70
  start-page: 124
  year: 1983
  end-page: 131
  ident: b0690
  article-title: Antibodies against polyethylene glycol produced in animals by immunization with monomethoxy polyethylene glycol modified proteins
  publication-title: Immunology
  contributor:
    fullname: Åkerblom
– volume: 383
  start-page: 2603
  year: 2020
  end-page: 2615
  ident: b0100
  article-title: Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine
  publication-title: N. Engl. J. Med.
  contributor:
    fullname: Group
– volume: 31
  year: 2019
  ident: b0615
  article-title: The crown and the scepter: roles of the protein corona in nanomedicine
  publication-title: Adv. Mater.
  contributor:
    fullname: Chen
– volume: 10
  start-page: 4421
  year: 2016
  end-page: 4430
  ident: b0620
  article-title: Regulation of macrophage recognition through the interplay of nanoparticle surface functionality and protein corona
  publication-title: ACS Nano
  contributor:
    fullname: Rottello
– volume: 131
  start-page: 4783
  year: 2009
  end-page: 4787
  ident: b0080
  article-title: PEG branched polymer for functionalization of nanomaterials with ultralong blood circulation
  publication-title: J. Am. Chem. Soc.
  contributor:
    fullname: Dai
– volume: 32
  start-page: 3435
  year: 2011
  end-page: 3446
  ident: b0485
  article-title: The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
  publication-title: Biomaterials
  contributor:
    fullname: Lam
– volume: 32
  start-page: 1907692
  year: 2020
  ident: b0805
  article-title: Engineered PD-L1-expressing platelets reverse new-onset type 1 diabetes
  publication-title: Adv. Mater.
  contributor:
    fullname: Gu
– volume: 114
  start-page: 1061
  year: 2001
  end-page: 1077
  ident: b0385
  article-title: Phagocytosis and the actin cytoskeleton
  publication-title: J. Cell Sci.
  contributor:
    fullname: Machesky
– volume: 14
  start-page: 4727
  year: 2020
  end-page: 4740
  ident: b0395
  article-title: RNA origami nanostructures for potent and safe anticancer immunotherapy
  publication-title: ACS Nano
  contributor:
    fullname: Chang
– volume: 31
  start-page: 1133
  year: 2020
  end-page: 1143
  ident: b0545
  article-title: Influence of gold nanoparticles with different surface charges on localization and monocyte behavior
  publication-title: Bioconjug. Chem.
  contributor:
    fullname: Tippayawat
– volume: 66
  start-page: 236
  year: 2020
  end-page: 245
  ident: b0410
  article-title: Unraveling the mechanobiology of immune cells
  publication-title: Curr. Opin. Biotechnol.
  contributor:
    fullname: Li
– volume: 107
  year: 2011
  ident: b0475
  article-title: Cellular uptake of elastic nanoparticles
  publication-title: Phys. Rev. Lett.
  contributor:
    fullname: Gao
– volume: 17
  start-page: 1
  year: 2020
  end-page: 9
  ident: b0645
  article-title: Altered levels of complement components associated with non-immediate drug hypersensitivity reactions
  publication-title: J. Immunotoxicol.
  contributor:
    fullname: Zhu
– volume: 51
  start-page: 861
  year: 2021
  end-page: 863
  ident: b0120
  article-title: Polyethylene glycol (PEG) is a cause of anaphylaxis to the Pfizer/BioNTech mRNA COVID-19 vaccine
  publication-title: Clin. Exp. Allergy
  contributor:
    fullname: Allergy
– volume: 40
  start-page: 616
  year: 2010
  end-page: 619
  ident: b0255
  article-title: Signaling by ROS drives inflammasome activation
  publication-title: Eur. J. Immunol.
  contributor:
    fullname: Martinon
– volume: 35
  start-page: 269
  year: 2014
  end-page: 277
  ident: b0025
  article-title: Particle shape dependence of CD8
  publication-title: Biomaterials
  contributor:
    fullname: Green
– volume: 530
  start-page: 422
  year: 2016
  end-page: 423
  ident: b0010
  article-title: Autoimmunity: Antigen-specific immunotherapy
  publication-title: Nature
  contributor:
    fullname: Wraith
– volume: 30
  year: 2019
  ident: b0600
  article-title: Polydopamine-based surface modification of paclitaxel nanoparticles for osteosarcoma targeted therapy
  publication-title: Nanotechnology
  contributor:
    fullname: Han
– volume: 384
  start-page: 403
  year: 2021
  end-page: 416
  ident: b0105
  article-title: Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine
  publication-title: N. Engl. J. Med.
  contributor:
    fullname: Group
– volume: 13
  start-page: eaaw9668
  year: 2021
  ident: b0680
  article-title: Modular immune-homeostatic microparticles promote immune tolerance in mouse autoimmune models
  publication-title: Sci. Transl. Med.
  contributor:
    fullname: Jin
– volume: 14
  start-page: 1
  year: 2012
  end-page: 16
  ident: b0175
  article-title: The effect of nanoparticle size, shape, and surface chemistry on biological systems
  publication-title: Annu. Rev. Biomed. Eng.
  contributor:
    fullname: Chan
– year: 2021
  ident: b0315
  article-title: TAK-101 Nanoparticles induce gluten-specific tolerance in celiac disease: a randomized, double-blind, placebo-controlled study
  publication-title: Gastroenterology
  contributor:
    fullname: Elhofy
– volume: 35
  start-page: 4477
  year: 2014
  end-page: 4488
  ident: b0220
  article-title: The role of macrophage phenotype in vascularization of tissue engineering scaffolds
  publication-title: Biomaterials
  contributor:
    fullname: Vunjak-Novakovic
– volume: 9
  start-page: 11461
  year: 2017
  end-page: 11471
  ident: b0420
  article-title: In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications
  publication-title: ACS Appl. Mater. Interfaces
  contributor:
    fullname: Borrós
– volume: 15
  start-page: 8
  year: 2017
  end-page: 10
  ident: b0640
  article-title: Complement activation turnover on surfaces of nanoparticles
  publication-title: Nano Today
  contributor:
    fullname: Simberg
– volume: 12
  start-page: 5834
  year: 2018
  end-page: 5847
  ident: b0630
  article-title: C1q-mediated complement activation and C3 opsonization trigger recognition of stealth poly(2-methyl-2-oxazoline)-coated silica nanoparticles by human phagocytes
  publication-title: ACS Nano
  contributor:
    fullname: Papini
– volume: 325
  start-page: 1101
  year: 2021
  end-page: 1102
  ident: b0110
  article-title: Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US-December 14, 2020-January 18, 2021
  publication-title: JAMA
  contributor:
    fullname: Su
– volume: 171
  start-page: 3988
  year: 2014
  end-page: 4000
  ident: b0160
  article-title: Immunosuppressive and anti-inflammatory properties of engineered nanomaterials
  publication-title: Br. J. Pharmacol.
  contributor:
    fullname: Dobrovolskaia
– volume: 109
  start-page: 469
  year: 2015
  end-page: 476
  ident: b0390
  article-title: Controlled one-on-one encounters between immune cells and microbes reveal mechanisms of phagocytosis
  publication-title: Biophys. J.
  contributor:
    fullname: Heinrich
– volume: 105
  start-page: 199
  year: 2005
  end-page: 212
  ident: b0495
  article-title: Enhanced antigen presentation and immunostimulation of dendritic cells using acid-degradable cationic nanoparticles
  publication-title: J. Controlled Release
  contributor:
    fullname: Frechet
– volume: 12
  start-page: 1
  year: 2021
  end-page: 18
  ident: b0785
  article-title: Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets
  publication-title: Nat. Commun.
  contributor:
    fullname: Scott
– volume: 51
  start-page: 34
  year: 1997
  end-page: 36
  ident: b0580
  article-title: The proton sponge: a trick to enter cells the viruses did not exploit, CHIMIA
  publication-title: Int. J. Chem.
  contributor:
    fullname: Behr
– volume: 115
  start-page: 11109
  year: 2015
  end-page: 11146
  ident: b0015
  article-title: Synthetic nanoparticles for vaccines and immunotherapy
  publication-title: Chem. Rev.
  contributor:
    fullname: Tokatlian
– volume: 108
  start-page: 586
  year: 2011
  end-page: 591
  ident: b0450
  article-title: Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: DeSimone
– volume: 17
  start-page: 1205
  year: 2016
  end-page: 1212
  ident: b0360
  article-title: Shape-dependent activation of cytokine secretion by polymer capsules in human monocyte-derived macrophages
  publication-title: Biomacromolecules
  contributor:
    fullname: Caruso
– volume: 9
  start-page: 10
  year: 2014
  end-page: 16
  ident: b0685
  article-title: Poly (carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production
  publication-title: Nano Today
  contributor:
    fullname: Jiang
– volume: 116
  start-page: 6107
  year: 2016
  end-page: 6132
  ident: b0780
  article-title: Discovery and optimization of materials using evolutionary approaches
  publication-title: Chem. Rev.
  contributor:
    fullname: Winkler
– volume: 15
  start-page: 406
  year: 2020
  end-page: 416
  ident: b0095
  article-title: Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Zhu
– volume: 46
  start-page: 622
  year: 2013
  end-page: 631
  ident: b0325
  article-title: Physicochemical properties determine nanomaterial cellular uptake, transport, and fate
  publication-title: Acc. Chem. Res.
  contributor:
    fullname: Zhao
– volume: 182
  start-page: 104
  year: 2018
  end-page: 113
  ident: b0670
  article-title: The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles
  publication-title: Biomaterials
  contributor:
    fullname: Wang
– volume: 27
  start-page: 7043
  year: 2015
  end-page: 7050
  ident: b0765
  article-title: Anticancer platelet-mimicking nanovehicles
  publication-title: Adv. Mater.
  contributor:
    fullname: Gu
– volume: 9
  start-page: 11800
  year: 2015
  end-page: 11811
  ident: b0790
  article-title: Neutrophil-mediated delivery of therapeutic nanoparticles across blood vessel barrier for treatment of inflammation and infection
  publication-title: ACS Nano
  contributor:
    fullname: Wang
– volume: 20
  start-page: 34
  year: 2010
  end-page: 50
  ident: b0655
  article-title: Complement and its role in innate and adaptive immune responses
  publication-title: Cell Res.
  contributor:
    fullname: Song
– volume: 222
  year: 2019
  ident: b0730
  article-title: Design of biodegradable nanoparticles to modulate phenotypes of antigen-presenting cells for antigen-specific treatment of autoimmune disease
  publication-title: Biomaterials
  contributor:
    fullname: Shea
– volume: 66
  start-page: 131
  year: 2020
  end-page: 139
  ident: b0195
  article-title: Engineering long-circulating nanomaterial delivery systems
  publication-title: Curr. Opin. Biotechnol.
  contributor:
    fullname: Cheng
– volume: 25
  start-page: 1159
  year: 2007
  end-page: 1164
  ident: b0185
  article-title: Exploiting lymphatic transport and complement activation in nanoparticle vaccines
  publication-title: Nat. Biotechnol.
  contributor:
    fullname: Hubbell
– volume: 12
  start-page: 10130
  year: 2018
  end-page: 10141
  ident: b0810
  article-title: Dense and dynamic polyethylene glycol shells cloak nanoparticles from uptake by liver endothelial cells for long blood circulation
  publication-title: ACS Nano
  contributor:
    fullname: Chen
– volume: 61
  start-page: 457
  year: 2009
  end-page: 466
  ident: b0320
  article-title: Effects of nanomaterial physicochemical properties on in vivo toxicity
  publication-title: Adv. Drug Delivery Rev.
  contributor:
    fullname: Forrest
– volume: 36
  start-page: 11
  year: 2016
  ident: b0625
  article-title: Complement-targeted therapy: development of C5- and C5a-targeted inhibition
  publication-title: Inflamm. Regen.
  contributor:
    fullname: Tsukamoto
– volume: 107
  start-page: 17939
  year: 2010
  end-page: 17944
  ident: b0200
  article-title: Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Farokhzad
– volume: 23
  start-page: 1313
  year: 2006
  end-page: 1323
  ident: b0665
  article-title: Complement activation by core-shell poly(isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide
  publication-title: Pharm. Res.
  contributor:
    fullname: Labarre
– volume: 47
  start-page: 4382
  year: 2011
  ident: b0230
  article-title: Size dependent macrophage responses and toxicological effects of Ag nanoparticles
  publication-title: Chem. Commun.
  contributor:
    fullname: Cheon
– volume: 371
  start-page: 145
  year: 2021
  end-page: 153
  ident: b0020
  article-title: A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
  publication-title: Science
  contributor:
    fullname: Sahin
– volume: 25
  start-page: 1467
  year: 2017
  end-page: 1475
  ident: b0125
  article-title: Lipid nanoparticle systems for enabling gene therapies
  publication-title: Mol. Ther.
  contributor:
    fullname: Hope
– volume: 12
  start-page: 52
  year: 2017
  ident: b0575
  article-title: The effect of superparamagnetic iron oxide nanoparticle surface charge on antigen cross-presentation
  publication-title: Nanoscale Res. Lett.
  contributor:
    fullname: Hu
– volume: 169
  start-page: 108
  year: 2017
  end-page: 119
  ident: b0290
  article-title: A DNA-based T cell receptor reveals a role for receptor clustering in ligand discrimination
  publication-title: Cell
  contributor:
    fullname: Vale
– volume: 9
  start-page: 399
  year: 2017
  end-page: 408
  ident: b0400
  article-title: Size, shape, and sequence-dependent immunogenicity of RNA nanoparticles
  publication-title: Mol. Ther. Nucleic Acids
  contributor:
    fullname: Guo
– volume: 18
  start-page: 1
  year: 2016
  end-page: 9
  ident: b0210
  article-title: Uptake of silver nanoparticles by monocytic THP-1 cells depends on particle size and presence of serum proteins
  publication-title: J. Nanopart. Res.
  contributor:
    fullname: Krystek
– volume: 19
  start-page: 477
  year: 2019
  end-page: 489
  ident: b0040
  article-title: The NLRP3 inflammasome: molecular activation and regulation to therapeutics
  publication-title: Nat. Rev. Immunol.
  contributor:
    fullname: Ting
– volume: 724
  start-page: 222
  year: 2012
  end-page: 238
  ident: b0310
  article-title: Multiple sclerosis
  publication-title: Adv. Exp. Med. Biol.
  contributor:
    fullname: Miller
– volume: 18
  start-page: 4309
  year: 2018
  end-page: 4321
  ident: b0405
  article-title: Structure and composition define immunorecognition of nucleic acid nanoparticles
  publication-title: Nano Lett.
  contributor:
    fullname: Afonin
– volume: 114
  start-page: 79
  year: 2017
  end-page: 101
  ident: b0005
  article-title: Delivering safer immunotherapies for cancer
  publication-title: Adv. Drug Delivery Rev.
  contributor:
    fullname: Irvine
– volume: 10
  start-page: 651
  year: 2014
  end-page: 660
  ident: b0595
  article-title: Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles
  publication-title: Nanomedicine (London, U. K.)
  contributor:
    fullname: Hourcade
– volume: 11
  start-page: 785
  year: 2010
  end-page: 797
  ident: b0650
  article-title: Complement: a key system for immune surveillance and homeostasis
  publication-title: Nat. Immunol.
  contributor:
    fullname: Lambris
– volume: 15
  start-page: 313
  year: 2020
  end-page: 320
  ident: b0525
  article-title: Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Siegwart
– volume: 13
  start-page: 1078
  year: 2018
  end-page: 1086
  ident: b0355
  article-title: Physical activation of innate immunity by spiky particles
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Xie
– volume: 32
  start-page: 2342
  year: 2011
  end-page: 2350
  ident: b0260
  article-title: Cytotoxicity of, and innate immune response to, size-controlled polypyrrole nanoparticles in mammalian cells
  publication-title: Biomaterials
  contributor:
    fullname: Jang
– volume: 11
  start-page: 372
  year: 2016
  end-page: 377
  ident: b0715
  article-title: Protein adsorption is required for stealth effect of poly (ethylene glycol)-and poly (phosphoester)-coated nanocarriers
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Wurm
– volume: 244
  start-page: 184
  year: 2016
  end-page: 193
  ident: b0085
  article-title: Anti-PEG antibodies in the clinic: current issues and beyond PEGylation
  publication-title: J. Controlled Release
  contributor:
    fullname: Jiang
– volume: 63
  start-page: 1168
  year: 2020
  end-page: 1182
  ident: b0165
  article-title: Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials
  publication-title: Sci. China Life Sci.
  contributor:
    fullname: Chen
– volume: 6
  year: 2020
  ident: b0375
  article-title: Neutrophils preferentially phagocytose elongated particles-An opportunity for selective targeting in acute inflammatory diseases
  publication-title: Sci. Adv.
  contributor:
    fullname: Eniola-Adefeso
– volume: 48
  start-page: 5140
  year: 2019
  end-page: 5176
  ident: b0330
  article-title: Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications
  publication-title: Chem. Soc. Rev.
  contributor:
    fullname: Chen
– volume: 136
  start-page: 253
  year: 2015
  end-page: 263
  ident: b0270
  article-title: Silver nanoparticles affect on gene expression of inflammatory and neurodegenerative responses in mouse brain neural cells
  publication-title: Environ. Res.
  contributor:
    fullname: Chuang
– volume: 12
  start-page: 877
  year: 2017
  end-page: 882
  ident: b0710
  article-title: Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Wang
– volume: 11
  start-page: 889
  year: 2010
  end-page: 896
  ident: b0215
  article-title: Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
  publication-title: Nat. Immunol.
  contributor:
    fullname: Mantovani
– volume: 17
  start-page: 7045
  year: 2017
  end-page: 7054
  ident: b0285
  article-title: Biologically inspired design of nanoparticle artificial antigen-presenting cells for immunomodulation
  publication-title: Nano Lett.
  contributor:
    fullname: Schneck
– volume: 28
  start-page: 17666
  year: 2012
  end-page: 17671
  ident: b0480
  article-title: Effects of nanoparticle charge and shape anisotropy on translocation through cell membranes
  publication-title: Langmuir
  contributor:
    fullname: Sureshkumar
– volume: 12
  start-page: 76
  year: 2016
  end-page: 82
  ident: b0695
  article-title: Modulation of immune response using engineered nanoparticle surfaces
  publication-title: Small
  contributor:
    fullname: Rotello
– volume: 15
  start-page: 9111
  year: 2021
  end-page: 9125
  ident: b0770
  article-title: Immunosuppressive nanoparticles for management of immune-related adverse events in liver
  publication-title: ACS Nano
  contributor:
    fullname: Wang
– volume: 8
  start-page: 1109
  year: 2017
  ident: b0065
  article-title: Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
  publication-title: Nat. Commun.
  contributor:
    fullname: Delogu
– volume: 12
  start-page: 1433
  year: 2018
  end-page: 1444
  ident: b0470
  article-title: Modulating phagocytic cell sequestration by tailoring nanoconstruct softness
  publication-title: ACS Nano
  contributor:
    fullname: Decuzzi
– volume: 10
  start-page: 1958
  year: 2019
  ident: b0800
  article-title: Expression, role, and regulation of neutrophil Fcγ receptors
  publication-title: Front. Immunol.
  contributor:
    fullname: Jönsson
– year: 2021
  ident: b0115
  article-title: Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines
  publication-title: J. Allergy Clin. Immunol.
  contributor:
    fullname: Milner
– volume: 13
  start-page: 558
  year: 2019
  end-page: 571
  ident: b0340
  article-title: The biodistribution and immuno-responses of differently shaped non-modified gold particles in zebrafish embryos
  publication-title: Nanotoxicology
  contributor:
    fullname: Vijver
– volume: 10
  start-page: 11290
  year: 2016
  end-page: 11303
  ident: b0365
  article-title: Tailoring nanostructure morphology for enhanced targeting of dendritic cells in atherosclerosis
  publication-title: ACS Nano
  contributor:
    fullname: Scott
– volume: 9
  start-page: 1
  year: 2018
  end-page: 12
  ident: b0370
  article-title: Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces
  publication-title: Nat. Commun.
  contributor:
    fullname: Li
– volume: 8
  start-page: 859
  year: 2008
  end-page: 865
  ident: b0145
  article-title: A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response
  publication-title: Nano Lett.
  contributor:
    fullname: Yan
– volume: 125
  start-page: 542
  year: 2015
  end-page: 552
  ident: b0465
  article-title: Cell rigidity and shape override CD47’s “self”-signaling in phagocytosis by hyperactivating myosin-II
  publication-title: Blood
  contributor:
    fullname: Discher
– volume: 11
  start-page: 375
  year: 2017
  end-page: 383
  ident: b0500
  article-title: Aerosol delivery of functionalized gold nanoparticles target and activate dendritic cells in a 3D lung cellular model
  publication-title: ACS Nano
  contributor:
    fullname: Rothen-Rutishauser
– volume: 21
  start-page: 677
  year: 2015
  end-page: 687
  ident: b0035
  article-title: Inflammasomes: mechanism of action, role in disease, and therapeutics
  publication-title: Nat. Med.
  contributor:
    fullname: Ting
– volume: 8
  start-page: 176
  year: 2012
  end-page: 184
  ident: b0520
  article-title: Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and Am Bisome
  publication-title: Nanomedicine (London U. K.)
  contributor:
    fullname: Barenholz
– volume: 33
  start-page: 2006160
  year: 2021
  ident: b0740
  article-title: Voluntary-opsonization-enabled precision nanomedicines for inflammation treatment
  publication-title: Adv. Mater.
  contributor:
    fullname: Wang
– volume: 6
  start-page: 1916
  year: 2018
  end-page: 1922
  ident: b0515
  article-title: Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy
  publication-title: Biomater. Sci.
  contributor:
    fullname: Wang
– volume: 30
  start-page: 1706780
  year: 2018
  ident: b0445
  article-title: Mechanobiological mimicry of helper T lymphocytes to evaluate cell-biomaterials crosstalk
  publication-title: Adv. Mater.
  contributor:
    fullname: Moshaverinia
– volume: 69
  start-page: 1
  year: 2015
  end-page: 11
  ident: b0675
  article-title: Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo
  publication-title: Biomaterials
  contributor:
    fullname: Wang
– volume: 116
  start-page: 14947
  year: 2019
  end-page: 14954
  ident: b0720
  article-title: Intravascular innate immune cells reprogrammed
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Shea
– volume: 2
  start-page: 249
  year: 2007
  end-page: 255
  ident: b0335
  article-title: Shape effects of filaments versus spherical particles in flow and drug delivery
  publication-title: Nat. Nanotechnol.
  contributor:
    fullname: Discher
– volume: 17
  start-page: 187
  year: 2018
  end-page: 194
  ident: b0455
  article-title: Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination
  publication-title: Nat. Mater.
  contributor:
    fullname: Ma
– volume: 28
  start-page: 5344
  year: 2007
  end-page: 5357
  ident: b0300
  article-title: Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response
  publication-title: Biomaterials
  contributor:
    fullname: Panda
– volume: 6
  start-page: 1700466
  year: 2017
  ident: b0605
  article-title: Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency
  publication-title: Adv. Healthcare Mater.
  contributor:
    fullname: Yu
– volume: 10
  start-page: 5536
  year: 2016
  end-page: 5542
  ident: b0530
  article-title: Surface charge controls the suborgan biodistributions of gold nanoparticles
  publication-title: ACS Nano
  contributor:
    fullname: Vachet
– volume: 28
  start-page: 7897
  year: 2010
  end-page: 7906
  ident: b0585
  article-title: Antigen delivery to dendritic cells by poly (propylene sulfide) nanoparticles with disulfide conjugated peptides: cross-presentation and T cell activation
  publication-title: Vaccine
  contributor:
    fullname: Swartz
– volume: 11
  start-page: 889
  issue: 10
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0215
  article-title: Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
  publication-title: Nat. Immunol.
  doi: 10.1038/ni.1937
  contributor:
    fullname: Biswas
– volume: 33
  start-page: 2006160
  issue: 3
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0740
  article-title: Voluntary-opsonization-enabled precision nanomedicines for inflammation treatment
  publication-title: Adv. Mater.
  doi: 10.1002/adma.202006160
  contributor:
    fullname: Li
– volume: 143
  start-page: 68
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0075
  article-title: Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
  publication-title: Adv. Drug Delivery Rev.
  doi: 10.1016/j.addr.2019.04.008
  contributor:
    fullname: Donahue
– volume: 30
  start-page: 1706780
  issue: 23
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0445
  article-title: Mechanobiological mimicry of helper T lymphocytes to evaluate cell-biomaterials crosstalk
  publication-title: Adv. Mater.
  doi: 10.1002/adma.201706780
  contributor:
    fullname: Hasani-Sadrabadi
– volume: 31
  start-page: 6867
  issue: 26
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0565
  article-title: The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.05.027
  contributor:
    fullname: Kedmi
– volume: 4
  start-page: 415
  issue: 6
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0440
  article-title: Material design for lymph node drug delivery
  publication-title: Nat. Rev. Mater.
  doi: 10.1038/s41578-019-0110-7
  contributor:
    fullname: Schudel
– volume: 7
  start-page: e1001068
  issue: 1
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0380
  article-title: Protrusive push versus enveloping embrace: computational model of phagocytosis predicts key regulatory role of cytoskeletal membrane anchors
  publication-title: PLoS Comput. Biol.
  doi: 10.1371/journal.pcbi.1001068
  contributor:
    fullname: Herant
– volume: 6
  start-page: 1700466
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0605
  article-title: Understanding the effect of surface chemistry of mesoporous silica nanorods on their vaccine adjuvant potency
  publication-title: Adv. Healthcare Mater.
  doi: 10.1002/adhm.201700466
  contributor:
    fullname: Yang
– volume: 9
  start-page: 399
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0400
  article-title: Size, shape, and sequence-dependent immunogenicity of RNA nanoparticles
  publication-title: Mol. Ther. Nucleic Acids
  doi: 10.1016/j.omtn.2017.10.010
  contributor:
    fullname: Guo
– volume: 10
  start-page: 4421
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0620
  article-title: Regulation of macrophage recognition through the interplay of nanoparticle surface functionality and protein corona
  publication-title: ACS Nano
  doi: 10.1021/acsnano.6b00053
  contributor:
    fullname: Saha
– volume: 6
  start-page: 219
  year: 2005
  ident: 10.1016/j.addr.2021.114039_b0030
  article-title: Innate and adaptive immunity: specificities and signaling hierarchies revisited
  publication-title: Nat. Immunol.
  doi: 10.1038/ni0205-219c
  contributor:
    fullname: Vivier
– volume: 21
  start-page: 677
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0035
  article-title: Inflammasomes: mechanism of action, role in disease, and therapeutics
  publication-title: Nat. Med.
  doi: 10.1038/nm.3893
  contributor:
    fullname: Guo
– volume: 6
  start-page: 1916
  issue: 7
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0515
  article-title: Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy
  publication-title: Biomater. Sci.
  doi: 10.1039/C8BM00463C
  contributor:
    fullname: Wang
– volume: 19
  start-page: 1945
  issue: 12
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0700
  article-title: Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics
  publication-title: Drug Discovery Today
  doi: 10.1016/j.drudis.2014.08.015
  contributor:
    fullname: Verhoef
– volume: 384
  start-page: 403
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0105
  article-title: Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa2035389
  contributor:
    fullname: Baden
– volume: 7
  start-page: 1700815
  issue: 4
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0240
  article-title: Cytokine profiling of primary human macrophages exposed to endotoxin-free graphene oxide: size-independent NLRP3 inflammasome activation
  publication-title: Adv. Healthcare Mater.
  doi: 10.1002/adhm.201700815
  contributor:
    fullname: Mukherjee
– volume: 9
  start-page: 11800
  issue: 12
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0790
  article-title: Neutrophil-mediated delivery of therapeutic nanoparticles across blood vessel barrier for treatment of inflammation and infection
  publication-title: ACS Nano
  doi: 10.1021/acsnano.5b05583
  contributor:
    fullname: Chu
– volume: 9
  start-page: 580
  issue: 3
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0555
  article-title: Effects of gold nanoparticles with different surface charges on cellular internalization and cytokine responses in monocytes
  publication-title: BioNanoScience
  doi: 10.1007/s12668-019-00638-8
  contributor:
    fullname: Srijampa
– volume: 30
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0600
  article-title: Polydopamine-based surface modification of paclitaxel nanoparticles for osteosarcoma targeted therapy
  publication-title: Nanotechnology
  doi: 10.1088/1361-6528/ab055f
  contributor:
    fullname: Zhao
– volume: 32
  start-page: 2342
  issue: 9
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0260
  article-title: Cytotoxicity of, and innate immune response to, size-controlled polypyrrole nanoparticles in mammalian cells
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.11.080
  contributor:
    fullname: Kim
– volume: 15
  start-page: 9111
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0770
  article-title: Immunosuppressive nanoparticles for management of immune-related adverse events in liver
  publication-title: ACS Nano
  doi: 10.1021/acsnano.1c02391
  contributor:
    fullname: Shen
– volume: 28
  start-page: 5344
  year: 2007
  ident: 10.1016/j.addr.2021.114039_b0300
  article-title: Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2007.08.015
  contributor:
    fullname: Kanchan
– volume: 17
  start-page: 187
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0455
  article-title: Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination
  publication-title: Nat. Mater.
  doi: 10.1038/nmat5057
  contributor:
    fullname: Xia
– volume: 9
  start-page: 1236
  issue: 2
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0135
  article-title: Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo
  publication-title: ACS Nano
  doi: 10.1021/nn504905q
  contributor:
    fullname: Mangraviti
– volume: 530
  start-page: 422
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0010
  article-title: Autoimmunity: Antigen-specific immunotherapy
  publication-title: Nature
  doi: 10.1038/nature17300
  contributor:
    fullname: Wraith
– volume: 131
  start-page: 4783
  year: 2009
  ident: 10.1016/j.addr.2021.114039_b0080
  article-title: PEG branched polymer for functionalization of nanomaterials with ultralong blood circulation
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja809086q
  contributor:
    fullname: Prencipe
– volume: 12
  start-page: 877
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0710
  article-title: Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2017.113
  contributor:
    fullname: Min
– volume: 31
  start-page: 3657
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0490
  article-title: Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.01.065
  contributor:
    fullname: He
– volume: 8
  start-page: 859
  issue: 3
  year: 2008
  ident: 10.1016/j.addr.2021.114039_b0145
  article-title: A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response
  publication-title: Nano Lett.
  doi: 10.1021/nl0730155
  contributor:
    fullname: Zhou
– volume: 13
  start-page: 558
  issue: 4
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0340
  article-title: The biodistribution and immuno-responses of differently shaped non-modified gold particles in zebrafish embryos
  publication-title: Nanotoxicology
  doi: 10.1080/17435390.2018.1564079
  contributor:
    fullname: van Pomeren
– volume: 8
  start-page: 176
  issue: 2
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0520
  article-title: Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and Am Bisome
  publication-title: Nanomedicine (London U. K.)
  contributor:
    fullname: Szebeni
– volume: 15
  start-page: 406
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0095
  article-title: Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/s41565-020-0648-y
  contributor:
    fullname: Wang
– year: 2020
  ident: 10.1016/j.addr.2021.114039_b0265
  article-title: Small-size silver nanoparticles stimulate neutrophil oxidative burst through an increase of intracellular calcium levels
  publication-title: World Acad. Sci. J.
  doi: 10.3892/wasj.2020.46
  contributor:
    fullname: Freitas
– volume: 14
  start-page: 4727
  issue: 4
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0395
  article-title: RNA origami nanostructures for potent and safe anticancer immunotherapy
  publication-title: ACS Nano
  doi: 10.1021/acsnano.0c00602
  contributor:
    fullname: Qi
– volume: 13
  start-page: eaaw9668
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0680
  article-title: Modular immune-homeostatic microparticles promote immune tolerance in mouse autoimmune models
  publication-title: Sci. Transl. Med.
  doi: 10.1126/scitranslmed.aaw9668
  contributor:
    fullname: Chen
– volume: 31
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0615
  article-title: The crown and the scepter: roles of the protein corona in nanomedicine
  publication-title: Adv. Mater.
  doi: 10.1002/adma.201805740
  contributor:
    fullname: Cai
– volume: 526
  start-page: 118
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0760
  article-title: Nanoparticle biointerfacing by platelet membrane cloaking
  publication-title: Nature
  doi: 10.1038/nature15373
  contributor:
    fullname: Hu
– year: 2021
  ident: 10.1016/j.addr.2021.114039_b0115
  article-title: Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines
  publication-title: J. Allergy Clin. Immunol.
  doi: 10.1016/j.jaci.2021.04.002
  contributor:
    fullname: Risma
– volume: 66
  start-page: 131
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0195
  article-title: Engineering long-circulating nanomaterial delivery systems
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2020.07.006
  contributor:
    fullname: Fan
– volume: 13
  start-page: 592
  year: 2013
  ident: 10.1016/j.addr.2021.114039_b0090
  article-title: Applications of nanotechnology for immunology
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri3488
  contributor:
    fullname: Smith
– volume: 724
  start-page: 222
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0310
  article-title: Multiple sclerosis
  publication-title: Adv. Exp. Med. Biol.
  doi: 10.1007/978-1-4614-0653-2_17
  contributor:
    fullname: Miller
– volume: 12
  start-page: 1
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0785
  article-title: Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-020-20886-7
  contributor:
    fullname: Vincent
– volume: 217
  start-page: 119299
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0510
  article-title: Charge-convertible polymers for improved tumor targeting and enhanced therapy
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2019.119299
  contributor:
    fullname: Li
– volume: 25
  start-page: 1467
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0125
  article-title: Lipid nanoparticle systems for enabling gene therapies
  publication-title: Mol. Ther.
  doi: 10.1016/j.ymthe.2017.03.013
  contributor:
    fullname: Cullis
– volume: 10
  start-page: 5536
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0530
  article-title: Surface charge controls the suborgan biodistributions of gold nanoparticles
  publication-title: ACS Nano
  doi: 10.1021/acsnano.6b02086
  contributor:
    fullname: Elci
– volume: 331
  start-page: 164
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0280
  article-title: PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2021.01.013
  contributor:
    fullname: Li
– volume: 18
  start-page: 1
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0210
  article-title: Uptake of silver nanoparticles by monocytic THP-1 cells depends on particle size and presence of serum proteins
  publication-title: J. Nanopart. Res.
  doi: 10.1007/s11051-016-3595-7
  contributor:
    fullname: Kettler
– volume: 9
  start-page: 10
  issue: 1
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0685
  article-title: Poly (carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production
  publication-title: Nano Today
  doi: 10.1016/j.nantod.2014.02.004
  contributor:
    fullname: Yang
– volume: 169
  start-page: 108
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0290
  article-title: A DNA-based T cell receptor reveals a role for receptor clustering in ligand discrimination
  publication-title: Cell
  doi: 10.1016/j.cell.2017.03.006
  contributor:
    fullname: Taylor
– volume: 182
  start-page: 104
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0670
  article-title: The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2018.08.022
  contributor:
    fullname: Wang
– volume: 107
  issue: 9
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0475
  article-title: Cellular uptake of elastic nanoparticles
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.107.098101
  contributor:
    fullname: Yi
– volume: 38
  start-page: 1142
  year: 2013
  ident: 10.1016/j.addr.2021.114039_b0045
  article-title: K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
  publication-title: Immunity
  doi: 10.1016/j.immuni.2013.05.016
  contributor:
    fullname: Muñoz-Planillo
– volume: 8
  start-page: 1109
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0065
  article-title: Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-017-01015-3
  contributor:
    fullname: Orecchioni
– volume: 18
  start-page: 4309
  issue: 7
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0405
  article-title: Structure and composition define immunorecognition of nucleic acid nanoparticles
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.8b01283
  contributor:
    fullname: Hong
– volume: 16
  start-page: 489
  issue: 4
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0425
  article-title: Designer vaccine nanodiscs for personalized cancer immunotherapy
  publication-title: Nat. Mater.
  doi: 10.1038/nmat4822
  contributor:
    fullname: Kuai
– volume: 19
  start-page: 477
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0040
  article-title: The NLRP3 inflammasome: molecular activation and regulation to therapeutics
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/s41577-019-0165-0
  contributor:
    fullname: Swanson
– volume: 5
  issue: 11
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0795
  article-title: Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.aax7964
  contributor:
    fullname: Zhang
– volume: 15
  start-page: 313
  issue: 4
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0525
  article-title: Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/s41565-020-0669-6
  contributor:
    fullname: Cheng
– volume: 136
  start-page: 253
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0270
  article-title: Silver nanoparticles affect on gene expression of inflammatory and neurodegenerative responses in mouse brain neural cells
  publication-title: Environ. Res.
  doi: 10.1016/j.envres.2014.11.006
  contributor:
    fullname: Huang
– volume: 5
  start-page: 1657
  issue: 3
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0505
  article-title: Differential uptake of functionalized polystyrene nanoparticles by human macrophages and a monocytic cell line
  publication-title: ACS Nano
  doi: 10.1021/nn2000756
  contributor:
    fullname: Lunov
– volume: 244
  start-page: 184
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0085
  article-title: Anti-PEG antibodies in the clinic: current issues and beyond PEGylation
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2016.06.040
  contributor:
    fullname: Zhang
– volume: 105
  start-page: 199
  year: 2005
  ident: 10.1016/j.addr.2021.114039_b0495
  article-title: Enhanced antigen presentation and immunostimulation of dendritic cells using acid-degradable cationic nanoparticles
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2005.02.027
  contributor:
    fullname: Kwon
– volume: 4
  start-page: 2100062
  issue: 8
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0775
  article-title: The combination of morphology and surface chemistry defines the immunological identity of nanocarriers in human blood
  publication-title: Adv. Ther.
  doi: 10.1002/adtp.202100062
  contributor:
    fullname: Vincent
– volume: 107
  start-page: 17939
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0200
  article-title: Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1011368107
  contributor:
    fullname: Kolishetti
– volume: 10
  start-page: 651
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0595
  article-title: Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles
  publication-title: Nanomedicine (London, U. K.)
  contributor:
    fullname: Pham
– volume: 118
  start-page: 1699
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0060
  article-title: Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing
  publication-title: Environ. Health Perspect.
  doi: 10.1289/ehp.1002201
  contributor:
    fullname: Cho
– volume: 18
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0435
  article-title: PD-L1–and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease
  publication-title: JCI insight
  contributor:
    fullname: Galea
– volume: 11
  start-page: 27615
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0750
  article-title: Biomaterial surface hydrophobicity-mediated serum protein adsorption and immune responses
  publication-title: ACS Appl. Mater. Interfaces
  doi: 10.1021/acsami.9b09900
  contributor:
    fullname: Visalakshan
– volume: 23
  start-page: 1313
  year: 2006
  ident: 10.1016/j.addr.2021.114039_b0665
  article-title: Complement activation by core-shell poly(isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide
  publication-title: Pharm. Res.
  doi: 10.1007/s11095-006-0069-0
  contributor:
    fullname: Bertholon
– volume: 2
  start-page: 249
  issue: 4
  year: 2007
  ident: 10.1016/j.addr.2021.114039_b0335
  article-title: Shape effects of filaments versus spherical particles in flow and drug delivery
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2007.70
  contributor:
    fullname: Geng
– volume: 11
  start-page: 785
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0650
  article-title: Complement: a key system for immune surveillance and homeostasis
  publication-title: Nat. Immunol.
  doi: 10.1038/ni.1923
  contributor:
    fullname: Ricklin
– volume: 109
  start-page: 469
  issue: 3
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0390
  article-title: Controlled one-on-one encounters between immune cells and microbes reveal mechanisms of phagocytosis
  publication-title: Biophys. J.
  doi: 10.1016/j.bpj.2015.06.042
  contributor:
    fullname: Heinrich
– volume: 14
  start-page: 2224
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0610
  article-title: Tuning nanoparticle interactions with ovarian cancer through layer-by-layer modification of surface chemistry
  publication-title: ACS Nano
  doi: 10.1021/acsnano.9b09213
  contributor:
    fullname: Correa
– volume: 114
  start-page: 79
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0005
  article-title: Delivering safer immunotherapies for cancer
  publication-title: Adv. Drug Delivery Rev.
  doi: 10.1016/j.addr.2017.05.011
  contributor:
    fullname: Milling
– volume: 13
  start-page: 1795
  issue: 14
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0350
  article-title: Influences of nanocarrier morphology on therapeutic immunomodulation
  publication-title: Nanomedicine (London U. K.)
  doi: 10.2217/nnm-2018-0052
  contributor:
    fullname: Frey
– volume: 221
  start-page: 1
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0660
  article-title: An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil(R), Caelyx(R), DOXOrubicin, and SinaDoxosome
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2015.11.021
  contributor:
    fullname: Wibroe
– volume: 36
  start-page: 160
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0295
  article-title: Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.4047
  contributor:
    fullname: Cheung
– volume: 14
  start-page: 2379
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0070
  article-title: Are nanotechnological approaches the future of treating inflammatory diseases?
  publication-title: Nanomedicine (London, U. K.)
  doi: 10.2217/nnm-2019-0159
  contributor:
    fullname: Rizzuto
– volume: 15
  start-page: 8
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0640
  article-title: Complement activation turnover on surfaces of nanoparticles
  publication-title: Nano Today
  doi: 10.1016/j.nantod.2017.03.001
  contributor:
    fullname: Moghimi
– volume: 31
  start-page: 8172
  issue: 32
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0560
  article-title: The promotion of type 1 T helper cell responses to cationic polymers in vivo via toll-like receptor-4 mediated IL-12 secretion
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.07.056
  contributor:
    fullname: Chen
– volume: 36
  start-page: 11
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0625
  article-title: Complement-targeted therapy: development of C5- and C5a-targeted inhibition
  publication-title: Inflamm. Regen.
  doi: 10.1186/s41232-016-0013-6
  contributor:
    fullname: Horiuchi
– volume: 25
  start-page: 1159
  year: 2007
  ident: 10.1016/j.addr.2021.114039_b0185
  article-title: Exploiting lymphatic transport and complement activation in nanoparticle vaccines
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt1332
  contributor:
    fullname: Reddy
– volume: 18
  start-page: 3814
  issue: 6
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0130
  article-title: Lipid nanoparticle formulations for enhanced co-delivery of siRNA and mRNA
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.8b01101
  contributor:
    fullname: Ball
– volume: 171
  start-page: 3988
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0160
  article-title: Immunosuppressive and anti-inflammatory properties of engineered nanomaterials
  publication-title: Br. J. Pharmacol.
  doi: 10.1111/bph.12722
  contributor:
    fullname: Ilinskaya
– volume: 9
  start-page: 11461
  issue: 13
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0420
  article-title: In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications
  publication-title: ACS Appl. Mater. Interfaces
  doi: 10.1021/acsami.7b00677
  contributor:
    fullname: Cifuentes-Rius
– volume: 12
  start-page: 387
  issue: 4
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0275
  article-title: Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2016.269
  contributor:
    fullname: Chen
– volume: 31
  start-page: 1133
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0545
  article-title: Influence of gold nanoparticles with different surface charges on localization and monocyte behavior
  publication-title: Bioconjug. Chem.
  doi: 10.1021/acs.bioconjchem.9b00847
  contributor:
    fullname: Srijampa
– volume: 116
  start-page: 6107
  issue: 10
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0780
  article-title: Discovery and optimization of materials using evolutionary approaches
  publication-title: Chem. Rev.
  doi: 10.1021/acs.chemrev.5b00691
  contributor:
    fullname: Le
– volume: 46
  start-page: 622
  year: 2013
  ident: 10.1016/j.addr.2021.114039_b0325
  article-title: Physicochemical properties determine nanomaterial cellular uptake, transport, and fate
  publication-title: Acc. Chem. Res.
  doi: 10.1021/ar300031y
  contributor:
    fullname: Zhu
– volume: 14
  start-page: 1801451
  issue: 42
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0170
  article-title: Size, shape, and protein corona determine cellular uptake and removal mechanisms of gold nanoparticles
  publication-title: Small
  doi: 10.1002/smll.201801451
  contributor:
    fullname: Ding
– volume: 70
  start-page: 124
  issue: 2
  year: 1983
  ident: 10.1016/j.addr.2021.114039_b0690
  article-title: Antibodies against polyethylene glycol produced in animals by immunization with monomethoxy polyethylene glycol modified proteins
  publication-title: Immunology
  contributor:
    fullname: Richter
– volume: 534
  start-page: 396
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0540
  article-title: Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
  publication-title: Nature
  doi: 10.1038/nature18300
  contributor:
    fullname: Kranz
– volume: 20
  start-page: 34
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0655
  article-title: Complement and its role in innate and adaptive immune responses
  publication-title: Cell Res.
  doi: 10.1038/cr.2009.139
  contributor:
    fullname: Dunkelberger
– volume: 113
  start-page: 13318
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0705
  article-title: One low-dose exposure of gold nanoparticles induces long-term changes in human cells
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1616400113
  contributor:
    fullname: Falagan-Lotsch
– volume: 12
  start-page: 52
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0575
  article-title: The effect of superparamagnetic iron oxide nanoparticle surface charge on antigen cross-presentation
  publication-title: Nanoscale Res. Lett.
  doi: 10.1186/s11671-017-1828-z
  contributor:
    fullname: Mou
– volume: 31
  start-page: 8188
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0590
  article-title: The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.07.067
  contributor:
    fullname: Dash
– volume: 371
  start-page: 145
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0020
  article-title: A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
  publication-title: Science
  doi: 10.1126/science.aay3638
  contributor:
    fullname: Krienke
– volume: 12
  start-page: 1433
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0470
  article-title: Modulating phagocytic cell sequestration by tailoring nanoconstruct softness
  publication-title: ACS Nano
  doi: 10.1021/acsnano.7b07797
  contributor:
    fullname: Palomba
– volume: 112
  start-page: 488
  issue: 2
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0570
  article-title: Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1422923112
  contributor:
    fullname: Fromen
– volume: 130
  start-page: 22
  year: 2008
  ident: 10.1016/j.addr.2021.114039_b0550
  article-title: Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2008.05.005
  contributor:
    fullname: Yan
– volume: 18
  start-page: 1298
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0050
  article-title: SR-B1 is a silica receptor that mediates canonical inflammasome activation
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2017.01.004
  contributor:
    fullname: Tsugita
– volume: 51
  start-page: 34
  year: 1997
  ident: 10.1016/j.addr.2021.114039_b0580
  article-title: The proton sponge: a trick to enter cells the viruses did not exploit, CHIMIA
  publication-title: Int. J. Chem.
  contributor:
    fullname: Behr
– volume: 17
  start-page: 1205
  issue: 3
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0360
  article-title: Shape-dependent activation of cytokine secretion by polymer capsules in human monocyte-derived macrophages
  publication-title: Biomacromolecules
  doi: 10.1021/acs.biomac.6b00027
  contributor:
    fullname: Chen
– volume: 114
  start-page: 1061
  year: 2001
  ident: 10.1016/j.addr.2021.114039_b0385
  article-title: Phagocytosis and the actin cytoskeleton
  publication-title: J. Cell Sci.
  doi: 10.1242/jcs.114.6.1061
  contributor:
    fullname: May
– volume: 13
  start-page: 4778
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0735
  article-title: Use of polymeric nanoparticle platform targeting the liver to induce treg-mediated antigen-specific immune tolerance in a pulmonary allergen sensitization model
  publication-title: ACS Nano
  doi: 10.1021/acsnano.9b01444
  contributor:
    fullname: Liu
– volume: 11
  start-page: 22849
  issue: 47
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0235
  article-title: The vacuolization of macrophages induced by large amounts of inorganic nanoparticle uptake to enhance the immune response
  publication-title: Nanoscale
  doi: 10.1039/C9NR08261A
  contributor:
    fullname: Cheng
– volume: 9
  start-page: 1
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0370
  article-title: Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-018-06869-9
  contributor:
    fullname: Cai
– volume: 66
  start-page: 236
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0410
  article-title: Unraveling the mechanobiology of immune cells
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2020.09.004
  contributor:
    fullname: Zhang
– volume: 34
  start-page: 455
  year: 2006
  ident: 10.1016/j.addr.2021.114039_b0535
  article-title: Normal structure, function, and histology of the spleen
  publication-title: Toxicol. Pathol.
  doi: 10.1080/01926230600867743
  contributor:
    fullname: Cesta
– volume: 63
  start-page: 1168
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0165
  article-title: Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials
  publication-title: Sci. China Life Sci.
  doi: 10.1007/s11427-020-1725-0
  contributor:
    fullname: Wang
– volume: 108
  start-page: 10980
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0755
  article-title: Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1106634108
  contributor:
    fullname: Hu
– volume: 4
  start-page: 5301
  issue: 9
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0245
  article-title: Cellular uptake, cytotoxicity, and innate immune response of silica-titania hollow nanoparticles based on size and surface functionality
  publication-title: ACS Nano
  doi: 10.1021/nn100561e
  contributor:
    fullname: Oh
– volume: 40
  start-page: 616
  issue: 3
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0255
  article-title: Signaling by ROS drives inflammasome activation
  publication-title: Eur. J. Immunol.
  doi: 10.1002/eji.200940168
  contributor:
    fullname: Martinon
– volume: 115
  start-page: 11109
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0015
  article-title: Synthetic nanoparticles for vaccines and immunotherapy
  publication-title: Chem. Rev.
  doi: 10.1021/acs.chemrev.5b00109
  contributor:
    fullname: Irvine
– volume: 9
  start-page: 1901223
  issue: 1
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0140
  article-title: Size-dependent EPR effect of polymeric nanoparticles on tumor targeting
  publication-title: Adv. Healthcare Mater.
  doi: 10.1002/adhm.201901223
  contributor:
    fullname: Kang
– volume: 20
  start-page: 1499
  issue: 3
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0430
  article-title: Sugar-nanocapsules imprinted with microbial molecular patterns for mRNA vaccination
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.9b03483
  contributor:
    fullname: Son
– volume: 16
  start-page: 1907609
  issue: 21
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0225
  article-title: Carbon nanomaterials promote M1/M2 macrophage activation
  publication-title: Small
  doi: 10.1002/smll.201907609
  contributor:
    fullname: Kinaret
– volume: 30
  start-page: 1217
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0305
  article-title: Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.2434
  contributor:
    fullname: Getts
– volume: 12
  start-page: 5834
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0630
  article-title: C1q-mediated complement activation and C3 opsonization trigger recognition of stealth poly(2-methyl-2-oxazoline)-coated silica nanoparticles by human phagocytes
  publication-title: ACS Nano
  doi: 10.1021/acsnano.8b01806
  contributor:
    fullname: Tavano
– volume: 18
  start-page: 3282
  issue: 5
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0150
  article-title: Activation of human natural killer cells by graphene oxide-templated antibody nanoclusters
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.8b01089
  contributor:
    fullname: Loftus
– volume: 34
  start-page: 33
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0055
  article-title: Nanoparticles and innate immunity: new perspectives on host defence
  publication-title: Semin. Immunol.
  doi: 10.1016/j.smim.2017.08.013
  contributor:
    fullname: Boraschi
– volume: 325
  start-page: 1101
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0110
  article-title: Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US-December 14, 2020-January 18, 2021
  publication-title: JAMA
  doi: 10.1001/jama.2021.1967
  contributor:
    fullname: Shimabukuro
– volume: 20
  start-page: 1126
  issue: 7
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0250
  article-title: Reactive oxygen species in inflammation and tissue injury
  publication-title: Antioxid. Redox Signaling
  doi: 10.1089/ars.2012.5149
  contributor:
    fullname: Mittal
– volume: 48
  start-page: 5140
  issue: 19
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0330
  article-title: Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications
  publication-title: Chem. Soc. Rev.
  doi: 10.1039/C9CS00011A
  contributor:
    fullname: Yang
– volume: 10
  start-page: 11290
  issue: 12
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0365
  article-title: Tailoring nanostructure morphology for enhanced targeting of dendritic cells in atherosclerosis
  publication-title: ACS Nano
  doi: 10.1021/acsnano.6b06451
  contributor:
    fullname: Yi
– volume: 134
  start-page: 3965
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0745
  article-title: Nanoparticle hydrophobicity dictates immune response
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja2108905
  contributor:
    fullname: Moyano
– volume: 16
  start-page: 87
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0155
  article-title: Metal nanomaterials: Immune effects and implications of physicochemical properties on sensitization, elicitation, and exacerbation of allergic disease
  publication-title: J. Immunotoxicol.
  doi: 10.1080/1547691X.2019.1605553
  contributor:
    fullname: Roach
– volume: 51
  start-page: 861
  year: 2021
  ident: 10.1016/j.addr.2021.114039_b0120
  article-title: Polyethylene glycol (PEG) is a cause of anaphylaxis to the Pfizer/BioNTech mRNA COVID-19 vaccine
  publication-title: Clin. Exp. Allergy
  doi: 10.1111/cea.13874
  contributor:
    fullname: Sellaturay
– volume: 14
  start-page: 1
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0175
  article-title: The effect of nanoparticle size, shape, and surface chemistry on biological systems
  publication-title: Annu. Rev. Biomed. Eng.
  doi: 10.1146/annurev-bioeng-071811-150124
  contributor:
    fullname: Albanese
– volume: 27
  start-page: 7043
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0765
  article-title: Anticancer platelet-mimicking nanovehicles
  publication-title: Adv. Mater.
  doi: 10.1002/adma.201503323
  contributor:
    fullname: Hu
– volume: 6
  issue: 24
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0375
  article-title: Neutrophils preferentially phagocytose elongated particles-An opportunity for selective targeting in acute inflammatory diseases
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.aba1474
  contributor:
    fullname: Safari
– volume: 12
  start-page: 2846
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0460
  article-title: Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting
  publication-title: ACS Nano
  doi: 10.1021/acsnano.8b00242
  contributor:
    fullname: Hui
– volume: 28
  start-page: 7897
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0585
  article-title: Antigen delivery to dendritic cells by poly (propylene sulfide) nanoparticles with disulfide conjugated peptides: cross-presentation and T cell activation
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2010.09.077
  contributor:
    fullname: Hirosue
– volume: 12
  start-page: 1096
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0190
  article-title: Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2017.170
  contributor:
    fullname: Du
– volume: 11
  start-page: 375
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0500
  article-title: Aerosol delivery of functionalized gold nanoparticles target and activate dendritic cells in a 3D lung cellular model
  publication-title: ACS Nano
  doi: 10.1021/acsnano.6b06061
  contributor:
    fullname: Fytianos
– volume: 11
  start-page: 372
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0715
  article-title: Protein adsorption is required for stealth effect of poly (ethylene glycol)-and poly (phosphoester)-coated nanocarriers
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2015.330
  contributor:
    fullname: Schöttler
– volume: 32
  start-page: 3435
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0485
  article-title: The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2011.01.021
  contributor:
    fullname: Xiao
– volume: 10
  start-page: 1958
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0800
  article-title: Expression, role, and regulation of neutrophil Fcγ receptors
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.01958
  contributor:
    fullname: Wang
– volume: 28
  start-page: 17666
  year: 2012
  ident: 10.1016/j.addr.2021.114039_b0480
  article-title: Effects of nanoparticle charge and shape anisotropy on translocation through cell membranes
  publication-title: Langmuir
  doi: 10.1021/la303449d
  contributor:
    fullname: Nangia
– volume: 35
  start-page: 269
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0025
  article-title: Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2013.09.050
  contributor:
    fullname: Sunshine
– volume: 69
  start-page: 1
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0675
  article-title: Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2015.07.048
  contributor:
    fullname: Du
– volume: 9
  start-page: 1294
  issue: 2
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0415
  article-title: Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo
  publication-title: ACS Nano
  doi: 10.1021/nn505125f
  contributor:
    fullname: Müllner
– volume: 11
  start-page: 5519
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0180
  article-title: Influence of size and shape on the anatomical distribution of endotoxin-free gold nanoparticles
  publication-title: ACS Nano
  doi: 10.1021/acsnano.7b00497
  contributor:
    fullname: Talamini
– volume: 9
  start-page: 1
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0205
  article-title: Block copolymer crystalsomes with an ultrathin shell to extend blood circulation time
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-018-05396-x
  contributor:
    fullname: Qi
– volume: 6
  start-page: 872
  issue: 7
  year: 2010
  ident: 10.1016/j.addr.2021.114039_b0345
  article-title: Shape-dependent cytotoxicity and proinflammatory response of poly(3,4-ethylenedioxythiophene) nanomaterials
  publication-title: Small
  doi: 10.1002/smll.200902074
  contributor:
    fullname: Oh
– volume: 17
  start-page: 1
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0645
  article-title: Altered levels of complement components associated with non-immediate drug hypersensitivity reactions
  publication-title: J. Immunotoxicol.
  doi: 10.1080/1547691X.2019.1695985
  contributor:
    fullname: Wang
– volume: 47
  start-page: 4382
  issue: 15
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0230
  article-title: Size dependent macrophage responses and toxicological effects of Ag nanoparticles
  publication-title: Chem. Commun.
  doi: 10.1039/c1cc10357a
  contributor:
    fullname: Park
– volume: 61
  start-page: 457
  year: 2009
  ident: 10.1016/j.addr.2021.114039_b0320
  article-title: Effects of nanomaterial physicochemical properties on in vivo toxicity
  publication-title: Adv. Drug Delivery Rev.
  doi: 10.1016/j.addr.2009.03.010
  contributor:
    fullname: Aillon
– volume: 32
  start-page: 1907692
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0805
  article-title: Engineered PD-L1-expressing platelets reverse new-onset type 1 diabetes
  publication-title: Adv. Mater.
  doi: 10.1002/adma.201907692
  contributor:
    fullname: Zhang
– volume: 12
  start-page: 76
  issue: 1
  year: 2016
  ident: 10.1016/j.addr.2021.114039_b0695
  article-title: Modulation of immune response using engineered nanoparticle surfaces
  publication-title: Small
  doi: 10.1002/smll.201502273
  contributor:
    fullname: Moyano
– volume: 108
  start-page: 586
  issue: 2
  year: 2011
  ident: 10.1016/j.addr.2021.114039_b0450
  article-title: Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1010013108
  contributor:
    fullname: Merkel
– volume: 12
  start-page: 10130
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0810
  article-title: Dense and dynamic polyethylene glycol shells cloak nanoparticles from uptake by liver endothelial cells for long blood circulation
  publication-title: ACS Nano
  doi: 10.1021/acsnano.8b04947
  contributor:
    fullname: Zhou
– volume: 13
  start-page: 1078
  issue: 11
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0355
  article-title: Physical activation of innate immunity by spiky particles
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/s41565-018-0274-0
  contributor:
    fullname: Wang
– volume: 35
  start-page: 4477
  issue: 15
  year: 2014
  ident: 10.1016/j.addr.2021.114039_b0220
  article-title: The role of macrophage phenotype in vascularization of tissue engineering scaffolds
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2014.02.012
  contributor:
    fullname: Spiller
– volume: 116
  start-page: 14947
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0720
  article-title: Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1820276116
  contributor:
    fullname: Park
– volume: 222
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0730
  article-title: Design of biodegradable nanoparticles to modulate phenotypes of antigen-presenting cells for antigen-specific treatment of autoimmune disease
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2019.119432
  contributor:
    fullname: Saito
– volume: 383
  start-page: 2603
  year: 2020
  ident: 10.1016/j.addr.2021.114039_b0100
  article-title: Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa2034577
  contributor:
    fullname: Polack
– volume: 125
  start-page: 542
  year: 2015
  ident: 10.1016/j.addr.2021.114039_b0465
  article-title: Cell rigidity and shape override CD47’s “self”-signaling in phagocytosis by hyperactivating myosin-II
  publication-title: Blood
  doi: 10.1182/blood-2014-06-585299
  contributor:
    fullname: Sosale
– volume: 29
  start-page: 976
  year: 2018
  ident: 10.1016/j.addr.2021.114039_b0635
  article-title: Complement activation by PEGylated gold nanoparticles
  publication-title: Bioconjug. Chem.
  doi: 10.1021/acs.bioconjchem.7b00793
  contributor:
    fullname: Quach
– volume: 300
  start-page: 185
  year: 2019
  ident: 10.1016/j.addr.2021.114039_b0725
  article-title: Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation
  publication-title: J. Controlled Release
  doi: 10.1016/j.jconrel.2019.02.025
  contributor:
    fullname: Saito
– volume: 17
  start-page: 7045
  year: 2017
  ident: 10.1016/j.addr.2021.114039_b0285
  article-title: Biologically inspired design of nanoparticle artificial antigen-presenting cells for immunomodulation
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.7b03734
  contributor:
    fullname: Hickey
– year: 2021
  ident: 10.1016/j.addr.2021.114039_b0315
  article-title: TAK-101 Nanoparticles induce gluten-specific tolerance in celiac disease: a randomized, double-blind, placebo-controlled study
  publication-title: Gastroenterology
  doi: 10.1053/j.gastro.2021.03.014
  contributor:
    fullname: Kelly
SSID ssj0012760
Score 2.5299635
SecondaryResourceType review_article
Snippet Nanomaterial physicochemical properties affect their immunomodulation. Here, size, surface charge, shape, rigidity and surface chemical composition of...
Immunomodulation is poised to revolutionize the treatment of cancer, autoimmune diseases, and many other inflammation-related disorders. The immune system in...
SourceID proquest
crossref
pubmed
elsevier
SourceType Aggregation Database
Index Database
Publisher
StartPage 114039
SubjectTerms Complement
Drug delivery
Drug Delivery Systems
Humans
Immunoengineering
Immunologic Factors - chemistry
Immunotherapy
Nanomaterials
Nanoparticles - chemistry
Title Tailoring the physicochemical properties of nanomaterials for immunomodulation
URI https://dx.doi.org/10.1016/j.addr.2021.114039
https://www.ncbi.nlm.nih.gov/pubmed/34742825
https://search.proquest.com/docview/2595119515
Volume 180
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8NAEB5KRfAiWl_1UVaQXmxsmtcmx1IsVbEUbKG3ZZNNoIJJ6ePQi7_dmWzSIqgHr2FDws7szLe7830DcKd4GEV24Bik1WXQ_S1pQEojkRHiD-UGZt6073XoDSbO89SdVqBXcmGorLKI_Tqm59G6eNIuZrM9n83ab6QjgruTqdXRunLEYMf0hz798Lkt8-hYPGcK02CDRhfEGV3jhYubNEGtDknmmtQw_Ofk9Bv4zJNQ_wgOC_TIuvoHj6ESpzXY1_0kNzVojrQQ9abFxjte1bLFmmy0k6jenMBwLGe69I4hAGT6eIN6Z-XiAWxOJ_QLklplWcJSmWaIa7WrMgS5bEakkuwjU0Xvr1OY9B_HvYFRdFYwItv1VoayLJkrq6tEJiZP_NC0It_3pC07keIqxPDJHQQ70lNxkHDlY9qKLMdOuB84bmKfQTXN0vgCmJIebnJ8k3PpOa4dySAI7TCQPCZlQBnX4b6cUjHXAhqirCx7F2QAQQYQ2gB1cMtZF9_cQGCE__O929JEAtcHXXrINM7WS4HbO7oqRdhWh3Ntu-1_2A53iLt7-c-vXsGBRWyI_ETmGqqrxTq-QYyyChu5EzZgr_v0Mhh-AbYu5Tg
link.rule.ids 315,783,787,4509,24128,27936,27937,45597,45691
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8NAEB6qInoRra_6XEG82NA0r02ORSzVPihYobdlk00ggklp66H_3plsYhHUg9eQZZed3dlvd-b7BuBW8TCK7MAxSKvLoPgtaUBKI5ER4g_lBmZRtG848nqvzvPUndbgoeLCUFpl6fu1Ty-8dfmlVc5ma5amrRfSEcHbydRqa125DdhCNBDg7tzqPPV7o69ggsULsjD9b1CDkjuj07xwf5MsqNUm1VyTaob_fD79hj-Lc6i7D3slgGQdPcYDqMVZHbZ1SclVHe7GWot61WSTNbVq0WR3bLxWqV4dwmgiU519xxADMv3CQeWzCv0ANqNH-jmprbI8YZnMcoS2erUyxLksJV5J_p6rsvzXEbx2HycPPaMsrmBEtustDWVZshBXV4lMTJ74oWlFvu9JW7YjxVWIHpQ7iHekp-Ig4crHkyuyHDvhfuC4iX0Mm1mexafAlPTwnuObnEvPce1IBkFoh4HkMYkDyrgB99WUipnW0BBVctmbIAMIMoDQBmiAW826-LYSBDr5P9vdVCYSuEUo7iGzOP9YCLzhUbQUkVsDTrTtvsZhO9wh-u7ZP3u9hp3eZDgQg6dR_xx2LSJHFA80F7C5nH_ElwhZluFVuSQ_AaEz5-w
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Tailoring+the+physicochemical+properties+of+nanomaterials+for+immunomodulation&rft.jtitle=Advanced+drug+delivery+reviews&rft.au=Deng%2C+Junjie&rft.au=Wang%2C+Jilong&rft.au=Shi%2C+Jiaqi&rft.au=Li%2C+Hongjun&rft.date=2022-01-01&rft.issn=0169-409X&rft.volume=180&rft.spage=114039&rft_id=info:doi/10.1016%2Fj.addr.2021.114039&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_addr_2021_114039
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0169-409X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0169-409X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0169-409X&client=summon