Can membrane excitation be described without a membrane capacity?

A simplified model of excitation is introduced in which the membrane capacity is ignored. It is shown that: (1) Threshold, action potentials, and strength-duration relation can be reproduced by a membrane without a capacity, even for a very simplified model. (2) The delayed build up of the sodium co...

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Bibliographic Details
Published inJournal of theoretical biology Vol. 57; no. 2; pp. 373 - 383
Main Author Colding-Jorgensen, Morten
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.1976
Subjects
Action Potentials
Animals
Axons
Cell Membrane - physiology
Decapodiformes
Electric Conductivity
Membrane Potentials
Models, Biological
Potassium - metabolism
Sodium - metabolism
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Summary:A simplified model of excitation is introduced in which the membrane capacity is ignored. It is shown that: (1) Threshold, action potentials, and strength-duration relation can be reproduced by a membrane without a capacity, even for a very simplified model. (2) The delayed build up of the sodium conductance can mimic a membrane capacity. (3) A constant potential stimulus can be used to reveal the influence of the membrane capacity, eventually combined with a feed back mechanism which reduces the effect of the capacity. (4) The effect of the membrane capacity depends on the ratio between the membrane time constant and the time constant for the fast conductance changes.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-5193
1095-8541
DOI:10.1016/0022-5193(76)90008-4