Remote tissue conditioning − an emerging approach for inducing body-wide protection against diseases of ageing

Highlights • Mild stress to a tissue elicits an endogenous response that enhances its resilience. • Two examples are brief ischemia and photobiomodulation with low-intensity light. • For both stresses, protection appears to spread beyond the site of application. • This phenomenon of indirect protect...

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Bibliographic Details
Published inAgeing research reviews Vol. 37; pp. 69 - 78
Main Authors Kim, Boaz, Brandli, Alice, Mitrofanis, John, Stone, Jonathan, Purushothuman, Sivaraman, Johnstone, Daniel M
Format Journal Article
LanguageEnglish
Published England 01.08.2017
Subjects
Aging
Chronic Disease - prevention & control
Humans
Internal Medicine
Ischemic Preconditioning
Low-Level Light Therapy
Neurology
Stress, Physiological
photobiomodulation
stress response
ischemic conditioning
remote
hormesis
resilience
Ischemic conditioning
Remote
Hormesis
Stress response
Photobiomodulation
Resilience
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Summary:Highlights • Mild stress to a tissue elicits an endogenous response that enhances its resilience. • Two examples are brief ischemia and photobiomodulation with low-intensity light. • For both stresses, protection appears to spread beyond the site of application. • This phenomenon of indirect protection is termed “remote tissue conditioning” (RIC). • RIC holds promise for prevention or treatment of chronic age-related diseases.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1568-1637
1872-9649
DOI:10.1016/j.arr.2017.05.005