Psychosis as a predictor of response to lithium maintenance treatment in bipolar affective disorder

Sixty-six bipolar I lithium clinic patients were studied for a history of psychotic symptoms at some time during the course of their illness. Agreement between different sources of information was calculated, and the patient population was divided into psychotic and non-psychotic subgroups. Probabil...

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Bibliographic Details
Published inJournal of affective disorders Vol. 1; no. 4; pp. 237 - 245
Main Authors Rosenthal, Norman E., Rosenthal, Leora N., Stallone, Frank, Fleiss, Joseph, Dunner, David L., Fieve, Ronald R.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.12.1979
Subjects
Actuarial Analysis
Adult
Bipolar Disorder - diagnosis
Bipolar Disorder - prevention & control
Bipolar Disorder - psychology
Delusions - diagnosis
Delusions - psychology
Double-Blind Method
Female
Follow-Up Studies
Hallucinations - diagnosis
Hallucinations - psychology
Humans
Lithium - therapeutic use
Lithium Carbonate
Male
Probability
Recurrence
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Summary:Sixty-six bipolar I lithium clinic patients were studied for a history of psychotic symptoms at some time during the course of their illness. Agreement between different sources of information was calculated, and the patient population was divided into psychotic and non-psychotic subgroups. Probability of remaining well on lithium for the different subgroups was analyzed by the life table method. Psychosis during mania appeared to be associated with especially good early lithium prophylaxis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0165-0327
1573-2517
DOI:10.1016/0165-0327(79)90010-7