Spatial reconstruction of human femoral atheromas showing regression
Reports of atherosclerotic changes in human subjects previously described have been based on evaluation of arteriographic edge contours. They imply unchanged roentgenographic and physiologic conditions, including identical patient positioning and vascular tone which cannot always be obtained in sequ...
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| Published in | The American journal of medicine Vol. 66; no. 5; pp. 784 - 789 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.05.1979
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| Subjects | |
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| Abstract | Reports of atherosclerotic changes in human subjects previously described have been based on evaluation of arteriographic edge contours. They imply unchanged roentgenographic and physiologic conditions, including identical patient positioning and vascular tone which cannot always be obtained in sequential studies. We have previously described the development of quantitative angiographic densitometry which permits measurement of vascular cross-sectional chord length distributions and areas, independent of rotational changes in vascular position. In this paper we report on application of the method to sequential femoral angiograms in two patients in whom there were significant increases in vascular cross-sectional area after a program of exercise and risk reduction. The method excludes interpretive errors due to circumferential changes in vascular tone. |
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| AbstractList | Reports of atherosclerotic changes in human subjects previously described have been based on evaluation of arteriographic edge contours. They imply unchanged roentgenographic and physiologic conditions, including identical patient positioning and vascular tone which cannot always be obtained in sequential studies. We have previously described the development of quantitative angiographic densitometry which permits measurement of vascular cross-sectional chord length distributions and areas, independent of rotational changes in vascular position. In this paper we report on application of the method to sequential femoral angiograms in two patients in whom there were significant increases in vascular cross-sectional area after a program of exercise and risk reduction. The method excludes interpretive errors due to circumferential changes in vascular tone. |
| Author | Crawford, Donald W. Sanmarco, Miguel E. Blankenhorn, David H. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/443253$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.7326/0003-4819-86-2-139 10.1111/j.1749-6632.1976.tb43368.x 10.1161/01.CIR.57.2.355 10.1097/00004424-197707000-00002 |
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| References | Hilal (BIB6) 1966 Wissler, Vesselinovitch (BIB1) 1976; 275 Crawford, Brooks, Barndt (BIB5) 1977; 12 Blankenhorn (BIB2) 1978; 47 Barndt, Blankenhorn, Crawford (BIB3) 1977; 86 Blankenhorn, Brooks, Selzer (BIB4) 1978; 57 Crawford, Brooks, Selzer (BIB7) 1977; 89 Crawford (10.1016/0002-9343(79)91117-3_BIB7) 1977; 89 Barndt (10.1016/0002-9343(79)91117-3_BIB3) 1977; 86 Hilal (10.1016/0002-9343(79)91117-3_BIB6) 1966 Blankenhorn (10.1016/0002-9343(79)91117-3_BIB4) 1978; 57 Crawford (10.1016/0002-9343(79)91117-3_BIB5) 1977; 12 Blankenhorn (10.1016/0002-9343(79)91117-3_BIB2) 1978; 47 Wissler (10.1016/0002-9343(79)91117-3_BIB1) 1976; 275 |
| References_xml | – volume: 12 start-page: 307 year: 1977 ident: BIB5 article-title: Measurement of atherosclerotic luminal irregularity and obstruction by radiographic densitometry publication-title: Invest Radiol contributor: fullname: Barndt – volume: 275 start-page: 363 year: 1976 ident: BIB1 article-title: Studies of regression of advanced atherosclerosis in experimental animals and man publication-title: Ann NY Acad Sci contributor: fullname: Vesselinovitch – volume: 47 start-page: 79 year: 1978 ident: BIB2 article-title: Reversibility of latent atherosclerosis. Studies by femoral angiography in humans publication-title: Mod Concepts Cardiovasc Dis contributor: fullname: Blankenhorn – year: 1966 ident: BIB6 article-title: Determination of the blood flow by a radiographic technique publication-title: PhD Dissertation contributor: fullname: Hilal – volume: 89 start-page: 378 year: 1977 ident: BIB7 article-title: Computer densitometry for angiographic assessment of arterial cholesterol content and gross pathology in human atherosclerosis publication-title: J Lab Clin Med contributor: fullname: Selzer – volume: 57 start-page: 355 year: 1978 ident: BIB4 article-title: Rate of atherosclerosis change during treatment of hyperlipoproteinemia publication-title: Circulation contributor: fullname: Selzer – volume: 86 start-page: 139 year: 1977 ident: BIB3 article-title: Regression and progression of early femoral atherosclerosis in treated hyperlipoproteinemic patients publication-title: Ann Intern Med contributor: fullname: Crawford – volume: 86 start-page: 139 year: 1977 ident: 10.1016/0002-9343(79)91117-3_BIB3 article-title: Regression and progression of early femoral atherosclerosis in treated hyperlipoproteinemic patients publication-title: Ann Intern Med doi: 10.7326/0003-4819-86-2-139 contributor: fullname: Barndt – volume: 275 start-page: 363 year: 1976 ident: 10.1016/0002-9343(79)91117-3_BIB1 article-title: Studies of regression of advanced atherosclerosis in experimental animals and man publication-title: Ann NY Acad Sci doi: 10.1111/j.1749-6632.1976.tb43368.x contributor: fullname: Wissler – volume: 47 start-page: 79 year: 1978 ident: 10.1016/0002-9343(79)91117-3_BIB2 article-title: Reversibility of latent atherosclerosis. Studies by femoral angiography in humans publication-title: Mod Concepts Cardiovasc Dis contributor: fullname: Blankenhorn – volume: 57 start-page: 355 year: 1978 ident: 10.1016/0002-9343(79)91117-3_BIB4 article-title: Rate of atherosclerosis change during treatment of hyperlipoproteinemia publication-title: Circulation doi: 10.1161/01.CIR.57.2.355 contributor: fullname: Blankenhorn – year: 1966 ident: 10.1016/0002-9343(79)91117-3_BIB6 article-title: Determination of the blood flow by a radiographic technique publication-title: PhD Dissertation contributor: fullname: Hilal – volume: 89 start-page: 378 year: 1977 ident: 10.1016/0002-9343(79)91117-3_BIB7 article-title: Computer densitometry for angiographic assessment of arterial cholesterol content and gross pathology in human atherosclerosis publication-title: J Lab Clin Med contributor: fullname: Crawford – volume: 12 start-page: 307 year: 1977 ident: 10.1016/0002-9343(79)91117-3_BIB5 article-title: Measurement of atherosclerotic luminal irregularity and obstruction by radiographic densitometry publication-title: Invest Radiol doi: 10.1097/00004424-197707000-00002 contributor: fullname: Crawford |
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| SubjectTerms | Adult Angiography Arteriosclerosis - diagnostic imaging Arteriosclerosis - therapy Densitometry Diet, Reducing Femoral Artery - diagnostic imaging Humans Male Middle Aged Myocardial Infarction - therapy Physical Exertion Risk |
| Title | Spatial reconstruction of human femoral atheromas showing regression |
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