Spatial reconstruction of human femoral atheromas showing regression

Reports of atherosclerotic changes in human subjects previously described have been based on evaluation of arteriographic edge contours. They imply unchanged roentgenographic and physiologic conditions, including identical patient positioning and vascular tone which cannot always be obtained in sequ...

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Bibliographic Details
Published inThe American journal of medicine Vol. 66; no. 5; pp. 784 - 789
Main Authors Crawford, Donald W., Sanmarco, Miguel E., Blankenhorn, David H.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.1979
Subjects
Adult
Angiography
Arteriosclerosis - diagnostic imaging
Arteriosclerosis - therapy
Densitometry
Diet, Reducing
Femoral Artery - diagnostic imaging
Humans
Male
Middle Aged
Myocardial Infarction - therapy
Physical Exertion
Risk
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Summary:Reports of atherosclerotic changes in human subjects previously described have been based on evaluation of arteriographic edge contours. They imply unchanged roentgenographic and physiologic conditions, including identical patient positioning and vascular tone which cannot always be obtained in sequential studies. We have previously described the development of quantitative angiographic densitometry which permits measurement of vascular cross-sectional chord length distributions and areas, independent of rotational changes in vascular position. In this paper we report on application of the method to sequential femoral angiograms in two patients in whom there were significant increases in vascular cross-sectional area after a program of exercise and risk reduction. The method excludes interpretive errors due to circumferential changes in vascular tone.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0002-9343
1555-7162
DOI:10.1016/0002-9343(79)91117-3