Assessment of cyclin D1 overexpression as a prognostic factor in soft tissue sarcomas : Role of laparoscopy and core needle biopsy

• Published in: Surgical endoscopy Vol. 19; no. 8; pp. 1120 - 1124
• Main Authors: MUSELLA, M, FAZIOLI, F, LOMBARDI, S, SERVODIO, C. I, DE MARTINO, C, IACONO, V, CIGALA, F, JOVINO, R
• Format: Journal Article
• Language: English
• Published: New York, NY Springer 01.08.2005; Springer Nature B.V
• Subjects: Biological and medical sciences; Biopsy; Biopsy, Needle; Cell cycle; Cyclin D1 - biosynthesis; Dermatology; Digestive system. Abdomen; Endoscopy; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Laparoscopy; Male; Medical prognosis; Medical sciences; Metastasis; Middle Aged; Patients; Prognosis; Sarcoma; Sarcoma - metabolism; Sarcoma - mortality; Sarcoma - pathology; Sarcoma - surgery; Soft Tissue Neoplasms - metabolism; Soft Tissue Neoplasms - mortality; Soft Tissue Neoplasms - pathology; Soft Tissue Neoplasms - surgery; Surgery; Survival Rate; Tumors; Tumors of the skin and soft tissue. Premalignant lesions; Cyclin Dl; Prognosis; Biopsy; Needle; Cyclin; Soft tissue sarcoma; Laparoscopy; Preoperative staging; Malignant tumor; Endoscopy; Preoperative; Soft tissue sarcomas

This study was designed to test cyclin D1 as a prognostic marker in patients with soft tissue sarcomas (STS), and to evaluate the usefulness of laparoscopy for determining cyclin D1 overexpression. The records of 62 patients with STS were collected: 28 with retroperitoneal STS (RSTS) and 34 with ext...