Primary hepatic mucosa-associated lymphoid tissue lymphoma complicated with atrial fibrillation: A case report and literature review

• Published in: Medicine (Baltimore) Vol. 103; no. 2; p. e36926
• Main Authors: Liu, Chenming, Liu, Yuxing, Zhang, Jiayao, Chai, Yingjie, Lu, Baochun, Tang, Haijun
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 12.01.2024
• Subjects: Atrial Fibrillation - complications; Clinical Case Report; Humans; Lymphoma, B-Cell, Marginal Zone - complications; Lymphoma, B-Cell, Marginal Zone - diagnosis; Lymphoma, B-Cell, Marginal Zone - drug therapy
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000036926

Primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is a rare malignant primary hepatic lymphoma. The sensible choice of treatment for patients with primary lymphoma combined with atrial fibrillation (AF) is controversial and challenging. The patient presented with both primary hepatic MALT lymphoma and AF, which was difficult to manage. Pathological and immunohistochemical examination are helpful for definitive diagnosis. Surgical resection and subsequent anticoagulant therapy are main treatment methods, and adjuvant therapy depends on the situation. Primary hepatic MALT lymphoma is easy to misdiagnosis due to a lack of typical symptoms and imaging signs. This case highlights for patients with primary hepatic MALT lymphoma combined with AF, toxicity caused by adjuvant chemotherapy should be fully considered, and careful selection should be made based on the general conditions and complications of patients.