Hepatocellular carcinoma: iodized-oil CT TNM classification

• Published in: American journal of roentgenology (1976) Vol. 167; no. 2; pp. 477 - 481
• Main Authors: Valls, C, Figueras, J, Jaurrieta, E, Sancho, C, Dominguez, J, Benasco, C, Moreno, P, Rafecas, A, Virgili, J, Castellsague
• Format: Journal Article
• Language: English
• Published: Leesburg, VA Am Roentgen Ray Soc 01.08.1996; American Roentgen Ray Society
• Subjects: Adult; Aged; Biological and medical sciences; Carcinoma, Hepatocellular - diagnostic imaging; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - therapy; Chemoembolization, Therapeutic; Contrast Media; Digestive system; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Iodized Oil; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - pathology; Liver Neoplasms - therapy; Male; Medical sciences; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Sensitivity and Specificity; Tomography, X-Ray Computed; Human; Radiodiagnosis; Liver; Hepatic disease; Transplantation; Malignant tumor; TNM-System; Prospective; Liver cell carcinoma; Surgery; Classification; Digestive diseases; Computerized axial tomography; Technique
• ISSN: 0361-803X; 1546-3141
• DOI: 10.2214/ajr.167.2.8686630

We conducted a prospective study to determine the efficacy of iodized-oil enhancement in CT for preoperative assessment of the T factor of the TNM classification in patients with hepatocellular carcinoma (HCC). Iodized-oil CT was performed as a part of preoperative staging in 28 patients with HCC. We determined the radiologic T factor. Pathologic correlation was obtained after orthotopic liver transplantation (n = 25) or autopsy (n = 3), and the histologic T factor was determined. The sensitivity of iodized-oil CT accurately distinguishing between stage-T4 tumors and tumors in stages T1-T3 was 88% (7/8) with a positive predictive value of 100% (7/7). Iodized-oil CT is useful for preoperatively assessing the T factor of the TNM classification in HCC, and it improves the accuracy of radiologic staging. Iodized-oil CT can help to better patients with HCC for orthotopic liver transplantation.