Estradiol-17β- progesterone and 5α-dihydrotestosterone receptors of uterine myometrium and myoma in the human subject

• Published in: Journal of steroid biochemistry Vol. 10; no. 6; pp. 615 - 622
• Main Authors: Tamaya, Teruhiko, Motoyama, Toshihiko, Ohono, Yousuke, Ide, Norimasa, Tsurusaki, Toshihide, Okada, Hiroji
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.06.1979
• Subjects: Adult; Cytosol - metabolism; Dihydrotestosterone - metabolism; Estradiol - metabolism; Female; Humans; Leiomyoma - metabolism; Mitotic Index; Myometrium - metabolism; Receptors, Androgen - isolation & purification; Receptors, Androgen - metabolism; Receptors, Estrogen - isolation & purification; Receptors, Estrogen - metabolism; Receptors, Progesterone - isolation & purification; Receptors, Progesterone - metabolism; Receptors, Steroid - metabolism; Uterine Neoplasms - metabolism; Uterus - metabolism; Estrogen receptor; estradiol-17β; androgen receptor; dihydrotestosterone; progesterone; dissociation constant; progesterone receptor
• ISSN: 0022-4731
• DOI: 10.1016/0022-4731(79)90513-2

Steroid receptors in human uterine myomas and the corresponding myometria were characterized and investigated to clarify their relation to tumor growth. The 248,800 g supernatant of tissue homogenates was used, in which steroid receptors were characterized and determined by Scatchard plot analysis u...