Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health

[Display omitted] Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of years, it has helped humans fight diseases and protect life, health, and reproduction. Nanomedicine, a newer discipline has evolved from exploitation of the unique nanoscale morphology an...

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Published inAdvanced drug delivery reviews Vol. 178; p. 113964
Main Authors Zhang, Jing, Hu, Kaili, Di, Liuqing, Wang, Penglong, Liu, Zhidong, Zhang, Jinming, Yue, Pengfei, Song, Wantong, Zhang, Jingwei, Chen, Tongkai, Wang, Zuhua, Zhang, Yongtai, Wang, Xiaoying, Zhan, Changyou, Cheng, Yung-Chi, Li, Xiang, Li, Quan, Fan, Jing-Yu, Shen, Youqing, Han, Jing-Yan, Qiao, Hongzhi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.11.2021
Subjects
Biological Products - chemistry
Biological Products - therapeutic use
Drug delivery
Herbal Medicine
Humans
Nanomedicine
Physiopathological regulation
Traditional herbal medicines
Traditional herbal medicines
Drug delivery
Physiopathological regulation
Nanomedicine
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Summary:[Display omitted] Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of years, it has helped humans fight diseases and protect life, health, and reproduction. Nanomedicine, a newer discipline has evolved from exploitation of the unique nanoscale morphology and is widely used in diagnosis, imaging, drug delivery, and other biomedical fields. Although THM and nanomedicine differ greatly in time span and discipline dimensions, they are closely related and are even evolving toward integration and convergence. This review begins with the history and latest research progress of THM and nanomedicine, expounding their respective developmental trajectory. It then discusses the overlapping connectivity and relevance of the two fields, including nanoaggregates generated in herbal medicine decoctions, the application of nanotechnology in the delivery and treatment of natural active ingredients, and the influence of physiological regulatory capability of THM on the in vivo fate of nanoparticles. Finally, future development trends, challenges, and research directions are discussed.
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2021.113964