Experimental porcine parvovirus infection of foetal pigs resulting in abortion, histological lesions and antibody formation

Three foetuses in each of 2 seronegative gilts were inoculated intramuscularly with porcine parvovirus. One gilt was killed 12 days post-infection (p.i.) and the other aborted 21 days p.i. Virus was recovered from both gilts and all foetuses and 12 of 16 foetuses developed HI antibody to parvovirus....

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Bibliographic Details
Published inJournal of comparative pathology Vol. 87; no. 4; pp. 539 - 549
Main Authors Hogg, G.G., Lenghaus, C., Forman, A.J.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.10.1977
Subjects
Abortion, Veterinary - pathology
Animals
Antibody Formation
Female
Fetal Diseases - immunology
Fetal Diseases - pathology
Fetal Diseases - veterinary
Fetus - pathology
Parvoviridae - immunology
Pregnancy
Swine
Swine Diseases - immunology
Swine Diseases - pathology
Virus Diseases - immunology
Virus Diseases - pathology
Virus Diseases - veterinary
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Summary:Three foetuses in each of 2 seronegative gilts were inoculated intramuscularly with porcine parvovirus. One gilt was killed 12 days post-infection (p.i.) and the other aborted 21 days p.i. Virus was recovered from both gilts and all foetuses and 12 of 16 foetuses developed HI antibody to parvovirus. All foetuses with antibody had histological lesions and 10 of 12 were smaller than normal. The main histological changes were perivascular, focal and diffuse infiltrations of mononuclear cells, particularly in the eye, brain, lung and mesentery, and reactive changes in lymphoid tissues.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0021-9975
1532-3129
DOI:10.1016/0021-9975(77)90060-3