Somatosensory temporal discrimination is impaired in fibromyalgia

• Published in: Journal of clinical neuroscience Vol. 60; pp. 44 - 48
• Main Authors: Gunendi, Zafer, Polat, Musa, Vuralli, Doga, Cengiz, Bulent
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.02.2019
• Subjects: Central sensitization; Cognitive dysfunction; Fibromyalgia; Somatosensory temporal discrimination; STD; SSSS; Fibromyalgia; Central sensitization; VAS; HADS; cTBS; FIQ; aSTDT; STDT; Somatosensory temporal discrimination; dSTDT; ISI; S1; Cognitive dysfunction; BMI
• ISSN: 0967-5868; 1532-2653
• DOI: 10.1016/j.jocn.2018.10.067

•Somatosensory temporal discrimination (STD) is prolonged in fibromyalgia patients.•Prolongation in STD correlates with severity of pain and other symptoms.•Impaired STD indicates alteration in higher-order sensory processing in fibromyalgia. Fibromyalgia is the prototypical central sensitivity syndrome which is associated with increased sensitivity to pain and other stimuli. In this study, we aimed to evaluate whether somatosensory temporal discrimination ability, which provides information about central processing of sensory stimuli, was impaired in patients with fibromyalgia. Fifteen patients with fibromyalgia and 15 healthy subjects participated in the study. Demographic characteristics of participants and severity for fatigue, sleep quality, cognitive symptoms, somatic symptoms and health-related quality of life in fibromyalgia patients were recorded. Somatosensory temporal discrimination thresholds were measured from the dorsum of the dominant hands of the participants by using a constant current stimulator (Medtronic, Keypoint). Patients with fibromyalgia had higher somatosensory temporal discrimination thresholds than healthy subjects (p < 0.001). There were significant correlations between STDTs and pain intensity, FIQ scores and symptom severity scale scores in fibromyalgia group (p = 0.006, r = 0.68; p = 0.037, r = 0.54; p = 0.017, r = 0.61 respectively). Somatosensory temporal discrimination ability is impaired in fibromyalgia patients compared to healthy subjects. Disrupted somatosensory temporal discrimination ability correlates with increased widespread pain and severity of other symptoms including fatigue, sleep quality, cognitive symptoms, somatic symptoms and decreased functional status. The impaired somatosensory temporal discrimination ability indicates an alteration in higher cognitive sensory processing in fibromyalgia patients.